Stroke Mortality Rates and Trends in Romania, 1994-2017

Ioacără, Sorin; Tiu, Cristina; Panea, Cristina; Nicolae, Horia; Sava, Elisabeta; Martin, Sorina; Fica, Simona

doi:10.1016/j.jstrokecerebrovasdis.2019.104431

Cited by 7 publications

(7 citation statements)

References 11 publications

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“…Also, this study is part of a bigger body of work regarding cardiovascular death. The already published data on stroke mortality shows similar trends [25].…”

Section: Discussionsupporting

confidence: 57%

Acute Myocardial Infarction Mortality Rates and Trends in Romania between 1994 and 2017

Ioacără

Popescu

Tenenbaum

et al. 2019

IJERPH

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Introduction: The current study aimed to assess recent acute myocardial infarction (AMI) mortality rates and trends in Romania between 1994 and 2017. This dataset is a necessity in the context of the current improvement of emergency protocols, medical addressability, and modernization of hospital infrastructure. Materials and Methods: The study is a retrospective analysis of an anonymized mortality database containing all deaths registered in Romania during 1994–2017. AMI crude mortality rates (CMR) and age-standardized mortality rates (ASMR) were calculated using the European Standard Population. Poisson regression was used for calculating the annual percentage change (APC) in mortality, subsequently used to make mortality predictions through the year 2030. Results: There were 197,152 AMI deaths in women (39.3% of total AMI), and 304,644 (60.7%) in men. Mortality rates were higher in men as compared with women for the entire time covered by the study. Based on the 1994–2017 ASMR dynamics, predictions for the year 2030 showed an overall AMI ASMR of 70.9 (95% CI 69.9–71.9), with gender analysis showing 46.8 (95% CI 45.8–47.9) in women and 104.1 (95% CI 102.3–105.8) in men. Conclusion: Acute myocardial infarction age-standardized mortality rates decreased significantly in Romania between 1994 and 2017 in close correlation to the implementation of national healthcare programs.

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“…Also, this study is part of a bigger body of work regarding cardiovascular death. The already published data on stroke mortality shows similar trends [25].…”

Section: Discussionsupporting

confidence: 57%

Acute Myocardial Infarction Mortality Rates and Trends in Romania between 1994 and 2017

Ioacără

Popescu

Tenenbaum

et al. 2019

IJERPH

Self Cite

View full text Add to dashboard Cite

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“…However, this is not the only condition that may be associated with mucormycosis. Patients with neoplasms, liver failure, neurologic disorders or hematological illnesses are at risk for opportunistic infections and may also present with such fungal infections (15). We must also keep in mind that patients must be made aware of the severity of the disease and the importance of their compliance to treatment, which may result in an overall increased survival (16).…”

Section: Resultsmentioning

confidence: 99%

Endoscopic assessment of sinonasal mucormycosis with SPIES: The ‘battlefield’ sign

et al. 2021

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Sinonasal mucormycosis is an extremely challenging pathology for the ear, nose and throat (ENT) surgeon from a therapeutic point of view. The disease affects immunocompromised patients and exhibits lethal potential. Although the diagnosis is relatively easy to suspect due to the distinctive clinical aspects which consists of black crusting present in the nasal fossae able to be confirmed by biopsy, the treatment requires resection of all affected tissue with safety limits. Due to the tendency of invasion associated with this fungal infection and taking into account the location involved (the sinonasal area) and the grave condition of these patients, it is extremely important to perform only the minimal resection necessary, but that includes all tissue infected by the fungus. This article presents a minimally invasive method of evaluation that can be performed during endoscopic surgical intervention and that aids the surgeon to better evaluate the affected area. It is associated with no additional risks for the patients, but it helps the surgeon to perform the intervention efficiently while not damaging healthy tissue. The authors consider that the method presented will aid the surgeon during the endoscopic surgical intervention in evaluating the lesion and resecting all the affected tissue while preserving healthy areas.

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“…Stroke is one of the main causes of mortality (21.64%) and morbidity (11.34%) in Romania, being a huge burden both for the caregivers and for the authorities (from a socio-economic point of view) [ 1 , 2 ]. For this reason, it was imperative to include in the research new biomarkers for the predictability and strict evaluation of stroke prognosis.…”

Section: Introductionmentioning

confidence: 99%

Prognostic markers for ischemic stroke – are they truly reliable?

Roman-FIlip

Catană

Mihăilă

2023

Medicine and Pharmacy Reports

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Background. Stroke is one of the leading causes of mortality and morbidity worldwide. Despite extensive research, to this date there is no panel of biomarkers for the prevention and prognosis of ischemic stroke and there is still much incomplete and insufficiently researched information. Aim. We conducted a prospective, observational study between January and June 2020. The main objective of this study was to clarify the role of inflammation markers, i.e. neutrophil/ lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), high-sensitivity C – reactive protein (hsCRP) in ischemic stroke and whether there is or not a correlation between these markers and carotid stenosis. Study design. In the study we included 150 subjects divided in two groups: study group – 100 subjects and control group – 50 subjects. Methods. Data collected during the research (at the time of patient admission): 1) biological sample: 5 ml of peripheral blood were collected in a vial with clot activator and separating gel, from which the following laboratory tests were performed: hsCRP, neutrophils, lymphocytes, platelets. NLR and PLR were subsequently calculated as the ratio of neutrophils to lymphocytes, respectively platelets and lymphocytes), 2) paraclinical examinations: extracranial carotid Doppler ultrasound examination. Results. The results were impressive: high-sensitivity C reactive protein (hsCRP), neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) were strongly, respectively moderately correlated with the severity of stroke (the severity being established with the NIHS (National Institute of Health Stroke) score. None of the inflammation markers included in the present study was correlated with carotid stenosis. Conclusion. hsCRP, NLR and PLR may potentially be prognostic markers for ischemic stroke, being of major help in preventing its possible complications.

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Stroke Mortality Rates and Trends in Romania, 1994-2017

Cited by 7 publications

References 11 publications

Acute Myocardial Infarction Mortality Rates and Trends in Romania between 1994 and 2017

Acute Myocardial Infarction Mortality Rates and Trends in Romania between 1994 and 2017

Endoscopic assessment of sinonasal mucormycosis with SPIES: The ‘battlefield’ sign

Prognostic markers for ischemic stroke – are they truly reliable?

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