Stroke in young adults: about 128 cases

Abstract

Ischemic stroke is rare in young adults, but it is genuinely a serious situation giving the fact that it touch a very active part of our society. We report a series of 128 cases. The purpose is to analyze the risk factors, etiologies and outcomes of ischemic stroke in young adults in Marrakesh. Retrospective study performed at the Neurology department Mohammed VI universitary hospital in Marrakesh interesting 128 patients. The diagnosis of ischemic stroke was assessed through clinical and radiological confrontation. Results: The age of our patients varied from 18 to 45 years old, 76 males and 52 females giving a male: female ratio of 1:46. Hypertension was the first risk factor involved with 63 (49.2%) cases, followed by smoking with 52 (40.6%) patients. The causes of ischemic stroke were characterized by the predominance of the cardio embolic origin with 43 (33.5%) cases, the existence of 14 (11%) cases of syphilitic arthritis, and the 52 (40.6%) cases of unknown etiologies. The authors stress the difficulties faced on supporting ischemic stroke in southern Morocco in particular when concerned by the etiological finding and the rehabilitation after the acute phase of the stroke. Our study points out the high incidence of embolic heart disease in our context. The lack of neurologists, low coverage of the population and the underestimation by physicians are factors that can explain why ischemic stroke remain undiagnosed.

Ischemic stroke in Morocco: A systematic review

“…Male predominance was described by Chraa et al (2014) with a sex ratio of 1.4 [40]. In addition, the Mbagui (2009) study did not show any significant difference between the two genders [42].…”

“…Concerning IS in early adulthood, four studies (n=4) included patients aged between 15 and 45 years old. The first was the study by Mbagui (2009) internal medicine under the age of 45 [39][40][41][42][43].…”

“…According to the studies of IS in young people, the average age ranged from 28.3 ± 4.2 to 39 years old (Extremes: 16-45 years old) [39][40][41][42][43].…”

“…Concerning the young population, the reported risk factors were smoking in (n = 4) studies (5-40.6%) [39][40][41][42], HBP in (n = 4) studies (8% -49.2%) [39][40][41][42][43], oral contraception in (n = 4) studies (12-31.2%) [39][40][41][42][43], cardiac diseases only by Chraa et al (2014) with a percentage of 17.9% [40], diabetes in (n = 4) studies (7.5-13.2%) [39][40][41][42][43], migraine in (n = 4) studies (1.5-24%) [39][40][41][42][43], dyslipidemia in (n = 3) studies (0-15.3%) [39,40,42], alcoholism in (n = 3) studies (5-8%) [39,40,42] and has observed a modest risk of IS with CC and C alleles. In addition, the same study explored also the risk of IS related to SG13S114 ALOX5AP showed a significant association with TT and T alleles.…”

Effectiveness of Cavinton® Comforte (Vinpocetin) in Therapy Patients with Arterial Hypertension, Atherosclerosis and Cerebral Venous Insufficiency

“…Артериальная гипертензия и атеросклероз -наиболее важные факторы риска развития хронических форм цереброваскулярных заболеваний (ХЦВЗ), являющихся причиной постепенного нарастания неврологических и психических расстройств у пациентов и представляющих собой важнейшую медико-социальную и экономическую проблему [1][2][3][4]. Кроме того, в последние годы наблюдается увеличение частоты обнаружения ХЦВЗ на фоне артериальной гипертензии и атеросклероза у лиц работоспособного возраста [5,6]. По данным эпидемиологического исследования, проведенного среди лиц 40-59 лет в открытой популяции Ульяновска, артериальная гипертензия стала причиной развития различных цереброваскулярных заболеваний в 46,7% случаев, из них 82,2% составили хронические формы [7].…”