String esophageal capsule endoscopy with real-time viewing improves visualization of the distal esophageal Z-line

Chen, Weisheng; Zhu, Lihuan; Li, Dazhou; Chen, Long; Wu, Yilong; Wang, Wen

doi:10.1097/meg.0000000000000038

Cited by 14 publications

(11 citation statements)

References 17 publications

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“…However, these results were not validated by another string capsule study, which showed sensitivity and specificity of 84% and 72%, respectively [ 106 ]. Nevertheless, it has been shown that string capsule endoscopy improves visualization of the distal esophagus, which may potentially have an impact on the detection of esophageal varices [ 107 ].…”

Section: Resultsmentioning

confidence: 99%

Νon-invasive screening for esophageal varices in patients with liver cirrhosis

Karatzas¹,

Konstantakis

Αγγελετοπούλου³

et al. 2018

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Esophageal varices are one of the main complications of liver cirrhosis. Upper gastrointestinal endoscopy is the gold standard for the detection of esophageal varices. Many less invasive methods for screening of varices have been investigated and the most recent Baveno VI guidelines suggest that endoscopy is not necessary in patients with liver stiffness <20 kPa and platelets >150,000/μL. A critical review of the literature was performed concerning non-invasive or minimally invasive methods of screening for esophageal varices. Liver and spleen elastography, imaging methods including computed tomography, magnetic resonance imaging and ultrasound, laboratory tests and capsule endoscopy are discussed. The accuracy of each method, and its advantages and limitations compared to endoscopy are analyzed. There are data to support the Baveno VI guidelines, but there is still a lack of large prospective studies and low specificity has been reported for the liver stiffness and platelet count combination. Spleen elastography has shown promising results, as there are data to support its superiority to liver elastography, but it needs further assessment. Computed tomography has shown high diagnostic accuracy and can be part of the diagnostic work up of cirrhotic patients in the future, including screening for varices.

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Section: Resultsmentioning

confidence: 99%

Νon-invasive screening for esophageal varices in patients with liver cirrhosis

Karatzas¹,

Konstantakis

Αγγελετοπούλου³

et al. 2018

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“…Chen et al introduced string ECE with real-time viewing [ 32 ]. They evaluated the cotton string-attached PillCam ESO capsule in 30 healthy volunteers with a real-time monitoring program.…”

Section: Additional Applicationsmentioning

confidence: 99%

“…They evaluated the cotton string-attached PillCam ESO capsule in 30 healthy volunteers with a real-time monitoring program. Compared with conventional ECE, the string-attached ECE showed improved Z-line visualization (at least two-quadrant visualization, 100.0% vs. 80.0%, p <0.001; at least three-quadrant visualization, 90.0% vs. 36.7%, p <0.001) [ 32 ].…”

Section: Additional Applicationsmentioning

confidence: 99%

Current and Future Use of Esophageal Capsule Endoscopy

2018

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Capsule endoscopy can be a diagnostic option for patients with esophageal diseases who cannot tolerate esophagogastroduodenoscopy.Functional modifications of the capsule allow for thorough examination of the esophagus. Esophageal capsule endoscopy has so farfailed to show sufficient performance to justify the replacement of traditional endoscopy for the diagnosis of esophageal diseasesbecause the esophagus has a short transit time and common pathologies appear near the esophagogastric junction. However,technological improvements are being introduced to overcome the limitations of capsule endoscopy, which is expected to become agood alternative to conventional endoscopy.

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“…16 The stringed esophageal wireless capsule endoscopy is considered to improve the operability and diagnostic yield in the identification of esophageal pathology. 17 In addition, the capability of the wireless device for providing the retrograde view of certain anatomical structures of the esophagus [e.g., the upper and lower esophageal sphincter (LES)] would be desirable for both clinical and research purposes.…”

Section: Introductionmentioning

confidence: 99%

“…If the capsule is attached to the strings as is described in Ref. 17, the mucus is trapped between the strings during the retrograde scanning and it makes capturing an image impossible. The retrograde scanning can provide new information on the esophageal pathology.…”

Section: Introductionmentioning

confidence: 99%

USB capsule endoscope for retrograde imaging of the esophagus

et al. 2020

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Significance: Endoscopes represent electro-optical devices that are used to visualize internal body cavities. The specialized endoscopic procedure of the upper gastrointestinal tract from the esophagus down to the duodenum is called an esophagogastroduodenoscopy. Aim: We bring our newly developed capsule endoscopy device as a promising alternative diagnostic method for visualization of the upper gastrointestinal tract. Approach: Capsule endoscopy has become an attractive method that uses a tiny wireless camera to take pictures of the digestive tract. Existing esophageal capsule endoscopy does not allow a retrograde view of the esophagus while retrograde scanning can provide information on the esophageal pathology. Results: In comparison to the existing esophageal capsule endoscopy, our system is much simpler and cheaper due to the need for fewer electronic devices. Moreover, its use is not limited by the capacity of the batteries used by existing capsule endoscopes. The new esophageal endoscopic system was created by combining the universal serial bus (USB) endoscope module with the thin power wires that are routed through the USB port to the computer. Conclusions: The endoscope was tested on a volunteer without any side effects such as nausea, belching, and general discomfort. The examination of the patient is performed in a sitting position and the patient discomfort during the examination is minimal so it can be performed without anesthesia.

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String esophageal capsule endoscopy with real-time viewing improves visualization of the distal esophageal Z-line

Abstract: Compared with ECE, SECE+RTV provides a better view of the distal esophagus in healthy individuals.

Cited by 14 publications

References 17 publications

Νon-invasive screening for esophageal varices in patients with liver cirrhosis

Νon-invasive screening for esophageal varices in patients with liver cirrhosis

Current and Future Use of Esophageal Capsule Endoscopy

USB capsule endoscope for retrograde imaging of the esophagus

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