Striatum and language processing: Where do we stand?

Jacquemot, Charlotte; Bachoud‐Lévi, Anne‐Catherine

doi:10.1016/j.cognition.2021.104785

Cited by 27 publications

(14 citation statements)

References 150 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, cortical hypometabolism is also suggested in cases with subcortical aphasia ( Halkar et al, 1997 ; de Boissezon et al, 2005 ; Sebastian et al, 2014 ). Additionally, specific cortical-subcortical circuits have been suggested to associate with language processing ( Teichmann et al, 2015 ; Akinina et al, 2019 ; Jacquemot and Bachoud-Lévi, 2021 ). Thus, multiple neural mechanisms might contribute to aphasia outcomes after chronic subcortical stroke.…”

Section: Discussionmentioning

confidence: 99%

Remote cortical atrophy and language outcomes after chronic left subcortical stroke with aphasia

et al. 2022

View full text Add to dashboard Cite

ObjectiveSubcortical stroke can cause a variety of language deficits. However, the neural mechanisms underlying subcortical aphasia after stroke remain incompletely elucidated. We aimed to determine the effects of distant cortical structures on aphasia outcomes and examine the correlation of cortical thickness measures with connecting tracts integrity after chronic left subcortical stroke.MethodsThirty-two patients and 30 healthy control subjects underwent MRI scanning and language assessment with the Western Aphasia Battery-Revised (WAB-R) subtests. Among patients, the cortical thickness in brain regions that related to language performance were assessed by the FreeSurfer software. Fiber tracts connecting the identified cortical regions to stroke lesions were reconstructed to determine its correlations with the cortical thickness measures across individual patient.ResultsCortical thickness in different parts of the left fronto-temporo-parietal (FTP) regions were positively related to auditory-verbal comprehension, spontaneous speech and naming/word finding abilities when controlling for key demographic variables and lesion size. Cortical thickness decline in the identified cortical regions was positively correlated with integrity loss of fiber tracts connected to stroke lesions. Additionally, no significant difference in cortical thickness was found across the left hemisphere between the subgroup of patients with hypoperfusion (HP) and those without HP at stroke onset.ConclusionsThese findings suggest that remote cortical atrophy independently predicts language outcomes in patients with chronic left subcortical stroke and aphasia and that cortical thinning in these regions might relate to integrity loss of fiber tracts connected to stroke lesions.

show abstract

Section: Discussionmentioning

confidence: 99%

Remote cortical atrophy and language outcomes after chronic left subcortical stroke with aphasia

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In the neurotypical brain, left dorsal striatal activation contributes to speech production ( Jacquemot and Bachoud-Lévi 2021 ). The goal of this study was to identify the neural mechanisms that support successful speech production in patients with focal left dorsal striatal damage affecting the putamen (POI).…”

Section: Discussionmentioning

confidence: 99%

Enhanced left superior parietal activation during successful speech production in patients with left dorsal striatal damage and error-prone neurotypical participants

et al. 2022

View full text Add to dashboard Cite

Functional imaging studies of neurotypical adults report activation in the left putamen during speech production. The current study asked how stroke survivors with left putamen damage are able to produce correct spoken responses during a range of speech production tasks. Using functional magnetic resonance imaging, activation during correct speech production responses was assessed in 5 stroke patients with circumscribed left dorsal striatal lesions, 66 stroke patient controls who did not have focal left dorsal striatal lesions, and 54 neurotypical adults. As a group, patients with left dorsal striatal damage (our patients of interest) showed higher activation than neurotypical controls in the left superior parietal cortex during successful speech production. This effect was not specific to patients with left dorsal striatal lesions as we observed enhanced activation in the same region in some patient controls and also in more error-prone neurotypical participants. Our results strongly suggest that enhanced left superior parietal activation supports speech production in diverse challenging circumstances, including those caused by stroke damage. They add to a growing body of literature indicating how upregulation within undamaged parts of the neural systems already recruited by neurotypical adults contributes to recovery after stroke.

show abstract

“…Similarly, many studies have shown that speech comprehension requires attention. This holds in particular for higher-level processes, such as syntactic integration and reanalysis and drawing inferences (for recent discussion and reviews see Cohen, Salony, Pallier, & Dehaene, 2021 ; Hubbard & Federmeier, 2021 ; Jacquemot & Bachaud-Levi, 2021 ; Wehbe et al, 2021 ).…”

Section: Concurrent Speech Planning and Listening Interfere With Each...mentioning

confidence: 99%

Timing in Conversation

Meyer

2023

Journal of Cognition

View full text Add to dashboard Cite

Turn-taking in everyday conversation is fast, with median latencies in corpora of conversational speech often reported to be under 300 ms. This seems like magic, given that experimental research on speech planning has shown that speakers need much more time to plan and produce even the shortest of utterances. This paper reviews how language scientists have combined linguistic analyses of conversations and experimental work to understand the skill of swift turn-taking and proposes a tentative solution to the riddle of fast turn-taking.

show abstract

Striatum and language processing: Where do we stand?

Cited by 27 publications

References 150 publications

Remote cortical atrophy and language outcomes after chronic left subcortical stroke with aphasia

Remote cortical atrophy and language outcomes after chronic left subcortical stroke with aphasia

Enhanced left superior parietal activation during successful speech production in patients with left dorsal striatal damage and error-prone neurotypical participants

Timing in Conversation

Contact Info

Product

Resources

About