Stress-responsive rhodamine bioconjugates for membrane-potential-independent mitochondrial live-cell imaging and tracking

Abstract

The 'power house' of the cell mitochondria upsurges significant interest in its investigation of imaging and mapping of the physiological processes. By utilizing sterol-modified rhodamine, we have performed live-cell imaging...

Single-Molecule Cholesterol Sensing by Integrating Silver Nanowire Propagating Plasmons and Graphene Oxide π-Plasmons on a Photonic Crystal-Coupled Emission Platform

“…Rhodamine-conjugated cholesterol is synthesized through the esterification of rhodamine B with cholesterol using DCC as per the previously published process. 53…”

Lutidine derivatives for live-cell imaging of the mitochondria and endoplasmic reticulum

“…For instance, a typical design for targeting the mitochondria and investigating their dynamics involves the incorporation of a cationic group, such as triphenylphosphonium (TPP + ), 11,12 a pyridinium group, and other substrates. [13][14][15][16][17][18][19][20][21][22] Similarly, for targeting the ER, the structural modifications include sulfonylurea, methyl sulfonamide motifs, or thiol-reactive functional groups such as halides. 18,19 The literature reveals many examples, majorly based on a naphthalimide scaffold bearing a sulfonamide functional moiety.…”

A multipurpose mitochondrial NIR probe for imaging ferroptosis and mitophagy

“…9 Considering the adverse physiological effects of MMP disruption, fluorescent probes that visualize mitochondria without dependence on MMP have been developed by enhancing lipophilicity. 19,24,25,42 Therefore, we developed Dp-A fluorophores based on the bis(styryl) architecture with dimethylamino phenyl (PP) and dimethylamino naphthyl (NP) groups. Both the styrenes are linked to a C-12 alkyl linker.…”