Stress Relaxation and Sleep Induction Effect of Fermented Sea Tangle Saccharina japonica and Oyster Crassostrea gigas Powder

Abstract

Sleep is an essential biological process of which the underlying regulatory mechanisms involve numerous anatomical structures and biochemical substances that can be compromised by stress and the immune system. Gamma aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the central nervous system (CNS). It is well established that activation of GABA A receptors promotes sleep. L. brevis BJ20 fermentation of sea tangle and oysters resulted in stress reduction and sleep inducing effects. This is the first study to report that GABA has the ability to induce sleep related hormones in mice; therefore, it has potential use as a natural sleep aid. These results suggested that sea tangle and oysters fermented by L. brevis BJ20 can be used as potential agents for stress reduction and sleep promotion.

Effect of Color Light Stimulation Using LED on Sleep Induction Time

“…Insomnia is a disorder in which the patient finds it difficult to fall asleep and to maintain the sleeping state, or whose sleep is often terminated, depriving him or her of a full rest [ 6 ]. According to DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, 4th edition), an American manual for classifying mental diseases, insomnia may occur in an acute form when the patient is exposed to psychological, social, or medical stress [ 7 ]. In fact, 78% of insomnia patients report that the onset of the disease was affected by stress [ 7 ].…”