Streptomycin for Urinary Tract Infections

A Comprehensive Treatment for Gonococcal and Non-Gonococcal Urethritis

“…Satisfactory results following streptomycin therapy of non-gonococcal urinary tract infections had been reported by Kane and Foley (1947) and Adcock and Plumb (1947), among others.…”

“…The effectiveness of streptomycin therapy in urinary tract infections and non-specific urethritis has also been described by Kane and Foley (1947), Adcock and Plumb (1947), Pulaski (1947), and Secretan (1952). Aureomycin, chloramphenicol, and terramycin possess greater in vitro activity against the gonococcus than streptomycin (Gocke and others, 1950), and have been shown to be effective in the treat-ment of gonorrhoea (Beinfield and others, 1951; Butler and others, 1952;Greaves and others, 1950;Robinson, 1950;Wright, Metzger, and others, 1951a;Wright, Prigot, and others, 1951b) and non-specific urethritis (Findlay and Willcox, 1951 ;Thomson, 1951 ;Tissot, 1951 ;Willcox and Findlay, 1952).…”

“…Streptomycin.-In urinary tract infections, Adcock and Plumb (1947) used streptomycin by intramuscular injection in divided doses to a total of from 2 5 g. over 21 days, to 18 g. over 9 days; they reported a high degree of success against infection with the Aerobacter group of organisms, but unsatisfactory results in five cases of infection with Ps. aeruginosa alone or with other organisms, and in one case of infection with E. coli.…”