Strategies in Development and Delivery of Nanotechnology Based Cosmetic Products

Ahmad, Usama; Ahmad, Zeeshan; Khan, Ahmed; Singh, Satya Prakash; Ahmad, Farhan Jalees

doi:10.1055/a-0582-9372

Cited by 43 publications

(25 citation statements)

References 56 publications

(60 reference statements)

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“…The particle sizes ranged from 123.9 ± 2.48 to 234.9 ± 2.66 nm (Table 1), which is in agreement with what has been reported in the literature, which is usually between 50 and 300 nm [21]. According to these results, the diameter of the nanoparticles was dependent on the amount of chitosan mass used in the synthesis of the nanoparticles.…”

Section: Resultssupporting

confidence: 89%

Adsorption of Vi Capsular Antigen of Salmonella Typhi in Chitosan–Poly (Methacrylic Acid) Nanoparticles

Silva

Júnior

et al. 2019

Polymers

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The development of a nanoparticulate system for the carrier antigen is now an important tool in the vaccination process, since a smaller number of doses is necessary for effective immunization. Thus, in this work a nanoparticulate system using polymers of chitosan and poly (methacrylic acid) (CS–PMAA) to adsorb the Vi antigen of Salmonella Typhi was developed. CS–PMAA nanoparticles with different proportions of chitosan and poly (methacrylic acid) were obtained and reached sizes from 123.9 ± 2.48 to 234.9 ± 2.66 nm, and spherical shapes were seen in transmission microscopy. At pH 7.2, the nanoparticles had a cationic surface charge that contributed to the adsorption of the Vi antigen. Qualitative analyses of the isolated Vi antigen were performed using Fourier-transform infrared spectroscopy, which indicated the presence of all the characteristic bands of the capsular polysaccharide, and nuclear magnetic resonance, which showed signals for the five hydrogens and the N-acetyl and O-acetyl groups which are characteristic of the Vi antigen structure. In the adsorption kinetics study, the Vi capsular antigen, contained in a phosphate buffer solution of pH 7.2, experienced 55% adsorption on the 1–1% (CS–PMAA) nanoparticles. The adsorption kinetics results showed the ability of the nanoparticulate system to adsorb the Vi antigen.

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Section: Resultssupporting

confidence: 89%

Adsorption of Vi Capsular Antigen of Salmonella Typhi in Chitosan–Poly (Methacrylic Acid) Nanoparticles

Silva

Júnior

et al. 2019

Polymers

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“…The benefit of nanotechnology has been recognized in preparing more efficient cosmetic skin care products 34 . Because of its beneficial effects, it is becoming increasingly popular in cosmetic products preparation, as some recent articles have suggested 35,36 …”

Section: Discussionmentioning

confidence: 99%

Favorableeffect of creams with skimmed donkey milk encapsulated in nanoliposomes on skin physiology

Kocic

Stanković

Tirant³

et al. 2020

Dermatologic Therapy

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The use of donkey milk has a long history in external dermal application for cosmetic and medical purposes. The encapsulation of different drugs into nanoliposomes and nutrients may have many benefits for the delivery of the targeted substance. The aim of the present study is to test creams with nanoliposomes encapsulated with skimmed donkey milk, reported in our registered patent, compared with effect of the placebo cream and the untreated skin. To investigate the effect of formulated cream, we have measured the electrical capacitance, transepidermal water loss and the skin pH value. The study included 15 healthy volunteers (11 women and 4 men). The patented creams exhibited satisfactory moisturizing properties very soon after application, while hydration was reached earlier in the spots treated with night cream. Transepidermal water loss slightly decreased only after 4 weeks of treatment in each of the spots assessed. The pH value was similar after each of the treatments. Tested creams may enhance the moisture of skin very soon after application, in this way potentially enable deeper permeation of phospholipids and essential proteins, without changing the pH. It may also contribute to additional anti‐aging effects.

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“…These nanostructures are being employed in various cosmeceutical products such as sunscreen, shampoos, anti-acne cream, and hair-styling gels [65]. The dendrimers have shown potential in the effective delivery of dermal preparations through the skin barrier [66]. Chauhan et al [67] first studied the skin penetration properties of G4-polyamidoamine dendrimers (PAMAM).…”

Section: Dendrimers In Cosmeticsmentioning

confidence: 99%

New Insights on Unique Features and Role of Nanostructured Materials in Cosmetics

Bilal

Iqbal

2020

Cosmetics

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The cosmetics industry has boomed in recent years as one of the markets that holds enormous growth potential. Among several industrial sectors, the cosmetics industry has considered nanotechnology-based principles and implemented in product management practices. Out of 1000 registered products available on the global market, up to 13% were referred to as products for cosmetic use. A large number of nanoscale materials with unique physicochemical properties are currently being used in the cosmetics formulations or recommended for future use as nano-systems or novel nanocarriers to encapsulate active ingredients for their efficient delivery through the skin barriers. These nano-systems have demonstrated potential in targeted-oriented drug delivery and offered remarkable features such as better stability, site-specificity, excellent encapsulation efficiency, prolonged action, enhanced skin penetration, and high drug-loading capability. Nevertheless, nanotoxicology research has raised concerns over the excessive use of nanomaterials/nanoparticles in cosmetics, as nanoparticles might enter the skin resulting in health problems. This review provides insights on the characteristic physicochemical features and the potential use of various nanostructured materials, including liposomes, noisome, nanoemulsions, nanoparticles, carbon nanomaterials (graphene, fullerenes), carbon nanotubes, dendrimers, and nanospheres in cosmeceuticals. Moreover, the regulatory aspects of nanomaterials in cosmetics, along with concluding remarks and outlook in this field, were also vetted.

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Strategies in Development and Delivery of Nanotechnology Based Cosmetic Products

Cited by 43 publications

References 56 publications

Adsorption of Vi Capsular Antigen of Salmonella Typhi in Chitosan–Poly (Methacrylic Acid) Nanoparticles

Adsorption of Vi Capsular Antigen of Salmonella Typhi in Chitosan–Poly (Methacrylic Acid) Nanoparticles

Favorableeffect of creams with skimmed donkey milk encapsulated in nanoliposomes on skin physiology

New Insights on Unique Features and Role of Nanostructured Materials in Cosmetics

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