Abstract:Statins as a lipid-lowering drug can selectively inhibit
3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and decrease
cholesterol synthesis effectively. With the improvement of nutritional
conditions, the demand for statins is increasing in global market. Due
to the rapid development of modern biotechnologies, the biosynthesis of
stains by microbial cell factory appears great advantages. It has the
advantages of simple operation and easy separation of products. This
review summarized the strategies o… Show more
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