Strategies for Optimization of the Production of Rosmarinic Acid in Salvia officinalis L. and Salvia dolomitica Codd Biomass with Several Biotechnological Approaches

Abstract

of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Large-Scale Plant Production of Lycium barbarum L. by Liquid Culture in Temporary Immersion System and Possible Application to the Synthesis of Bioactive Substance

“…In particular, among the phytochemicals, phenolic and flavonoid compounds are the most interesting and investigated [1,33]. In this context, tissue culture is a valuable technique to produce secondary metabolites, and many studies showed the improvements that can be obtained in many species such as, in the same Lamiaceae family, sage [3] and oregano [34]. The advantage to produce antioxidants by goji in vitro culture was also underlined by Osman et al [21] and Dutu et al [35] on 2-month old plantlets, using the conventional micropropagation.…”

“…Plant tissue culture is considered a valuable technique for the production of bioactive compounds [2,3], as an alternative way to the exploit its natural habitat where, in addition, its harvesting is influenced by the plant growth stage, environmental stress, nutrition, and plant genetic [4].…”

“…Plant tissue culture is considered a valuable technique for the production of bioactive compounds [ 2 , 3 ], as an alternative way to the exploit its natural habitat where, in addition, its harvesting is influenced by the plant growth stage, environmental stress, nutrition, and plant genetic [ 4 ]. However, micropropagation of plants is time consuming, labor intensive and expensive [ 5 ], and is commercially exploitable when the production cycle is made economically advantageous.…”

Plant cell culture as emerging technology for production of active cosmetic ingredients

“…Because plant cells are considered totipotent, they have the potential to express the full genetic machinery coded in the nucleus, and thus, they are able to produce the full spectrum of characteristic secondary metabolites, found in mother plants. This is very important advantage especially for the production of rare bioactive compounds, as resveratrol, paclitaxel or terpenoids, which are usually found in low concentrations in plants and their isolation and purification requires the processing of large amounts plant biomass [21][22][23][24][25]. Moreover, in vitro cultured plant cells are characterized with fast growth, and the ability to accumulate large amount of uniform biomass for a short period of time [19,20].…”

“…Moreover, in vitro cultured plant cells are characterized with fast growth, and the ability to accumulate large amount of uniform biomass for a short period of time [19,20]. This is very important advantage especially for the production of rare bioactive compounds, as resveratrol, paclitaxel or terpenoids, which are usually found in low concentrations in plants and their isolation and purification requires the processing of large amounts plant biomass [21][22][23][24][25]. Additionally, plant cell culture technology offers a reliable and powerful production platform for continuous supply of contamination-free, phytochemically uniform biomass from herbal, aromatic, medicinal, and even from rare and threatened plant species [26].…”