Strain-rate dependent material properties of the porcine and human kidney capsule

Snedeker, Jess G.; Niederer, Peter F.; Schmidlin, F.; Farshad, M.; Demetropoulos, Constantine K.; Lee, J.B.; Yang, King H.

doi:10.1016/j.jbiomech.2004.05.036

Cited by 106 publications

(101 citation statements)

References 21 publications

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“…34 Having sufficient mechanical integrity to resist handling during implantation and in vivo loading is a requisite for scaffolding materials. 28 It has been reported that kidney 35 and liver 36,37 tissues have the maximum stress of 9.0 and 9.82 MPa, respectively. The PVA sponge fabricated in this study presented a maximum stress of 9.79 MPa, therefore, …”

Section: R E T R a C T E Dmentioning

confidence: 99%

RETRACTED: Fabrication and mechanical characterization of a polyvinyl alcohol sponge for tissue engineering applications

2013

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Polyvinyl alcohol (PVA) sponges are widely used for clinical applications, including ophthalmic surgical treatments, wound healing and tissue engineering. There is, however, a lack of sufficient data on the mechanical properties of PVA sponges. In this study, a biomechanical method is used to characterize the elastic modulus, maximum stress and strain as well as the swelling ratio of a fabricated PVA sponge (P-sponge) and it is compared with two commercially available PVA sponges (CENEFOM and EYETEC). The results indicate that the elastic modulus of the P-sponge is 5.32% and 13.45% lower than that of the CENEFOM and EYETEC sponges, while it bears 4.11% more and 10.37% less stress compared to the CENEFOM and EYETEC sponges, respectively. The P-sponge shows a maximum strain of 32% more than the EYETEC sponge as well as a 26.78% higher swelling ratio, which is a significantly higher absorbency compared to the CENEFOM. It is believed that the results of this study would help for a better understanding of the extension, rupture and swelling mechanism of PVA sponges, which could lead to crucial improvement in the design and application of PVAbased materials in ophthalmic and plastic surgeries as well as wound healing and tissue engineering.

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Section: R E T R a C T E Dmentioning

confidence: 99%

RETRACTED: Fabrication and mechanical characterization of a polyvinyl alcohol sponge for tissue engineering applications

2013

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“…Rats were skeletally mature (17 weeks), male, and weight matched. Specimens were extracted from the tail and clamped immediately before mechanical testing using previously described soft tissue mounting techniques (Snedeker et al, 2005).…”

Section: Experimental Procedures Rat Tail Tendon Fascicle Preparationmentioning

confidence: 99%

Evidence against proteoglycan mediated collagen fibril load transmission and dynamic viscoelasticity in tendon

Fessel¹,

Snedeker²

2009

Matrix Biology

138

112

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Evidence against proteoglycan mediated collagen fibril load transmission and dynamic viscoelasticity in tendon Fessel, G; Snedeker, J G Fessel, G; Snedeker, J G (2009 The glycosaminoglycan (GAG) dermatan sulphate and chondroitin sulphate side-chains of small leucine-rich proteoglycans have been increasingly posited to act as molecular cross links between adjacent collagen fibrils and to directly contribute to tendon elasticity. GAGs have also been implicated in tendon viscoelasticity, supposedly affecting frictional loss during elongation or fluid flow through the extra cellular matrix.The current study sought to systematically test these theories of tendon structure-function by investigating the mechanical repercussions of enzymatic depletion of GAG complexes by chondroitinase ABC in a reproducible tendon structure-function model (rat tail fascicles). The extent of GAG removal (at least 93%) was verified by relevant spectrophotometric assays and transmission electron microscopy. Dynamic viscoelastic tensile tests on GAG depleted rat tail tendon fascicle were not mechanically different from controls in storage modulus (elastic behavior) over a wide range of strain-rates (0.05, 0.5, and 5% change in length per second) in either the linear or nonlinear regions of the material curve. Loss modulus (viscoelastic behavior) was only affected in the nonlinear region at the highest strain rate, and even this effect was marginal (19% increased loss modulus, p=0.035). Thus glycosaminoglycan chains of small leucine rich proteoglycans do not appear to mediate dynamic elastic behavior nor do they appear to regulate the dynamic viscoelastic properties in rat tail tendon fascicles.

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“…Several groups (Dunn and Silver 1983;Hof 2003;Huang et al 2005;Klein et al 2005;Kuo et al 2001;Lally et al 2004;Provenzano et al 2002;Silver et al 2001;Suki et al 1994;Wu et al 2003) have reported findings on mechanical properties of some soft tissues, but most of their studies were focused on tendons, ligaments, cartilage, skin, muscles, lungs, or arteries, which, to some extent, have active force-generating mechanical properties. In contrast, just a few publications (Arbogast and Margulies 1998;Chen et al 1996;Darvish and Crandall 2001;Krouskop et al 1998;Liu and Bilston 2000;Nasseri et al 2002;Phipps et al 2005aPhipps et al , 2005bSnedeker et al 2005;Yang and Church 2006;Yeh et al 2002) presented quantitative results on the viscoelastic behavior of tissues such as brain, breast, prostate, liver, or kidney. Liu and Bilston (2000) studied the viscoelastic properties of bovine liver tissue with three testing methods: shear strain sweep oscillation, shear stress relaxation, and shear oscillation.…”

Section: Introductionmentioning

confidence: 99%

“…The mean Young's modulus values were 9.9 kPa and 6.6 kPa, respectively (Kemper et al 2004). Significant discrepancies were also found on the reported stiffness of kidney tissue (Erkamp et al 1998;Kruse et al 2000;Nasseri et al 2002;Snedeker et al 2005). The divergent reports of soft tissue properties are mainly caused by the different choices of testing techniques, tissue models, compression frequencies, temperature, sample variation, and other experimental factors.…”

Section: Introductionmentioning

confidence: 99%

Congruence of Imaging Estimators and Mechanical Measurements of Viscoelastic Properties of Soft Tissues

Zhang

Castaneda

et al. 2007

Ultrasound in Medicine & Biology

101

112

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Biomechanical properties of soft tissues are important for a wide range of medical applications, such as surgical simulation and planning and detection of lesions by elasticity imaging modalities. Currently, the data in the literature is limited and conflicting. Furthermore, to assess the biomechanical properties of living tissue in vivo, reliable imaging-based estimators must be developed and verified. For these reasons we developed and compared two independent quantitative methods -crawling wave estimator (CRE) and mechanical measurement (MM) for soft tissue characterization. The CRE method images shear wave interference patterns from which the shear wave velocity can be determined and hence the Young's modulus can be obtained. The MM method provides the complex Young's modulus of the soft tissue from which both elastic and viscous behavior can be extracted. This article presents the systematic comparison between these two techniques on the measurement of gelatin phantom, veal liver, thermal-treated veal liver, and human prostate. It was observed that the Young's moduli of liver and prostate tissues slightly increase with frequency. The experimental results of the two methods are highly congruent, suggesting CRE and MM methods can be reliably used to investigate viscoelastic properties of other soft tissues, with CRE having the advantages of operating in nearly real time and in situ.

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Strain-rate dependent material properties of the porcine and human kidney capsule

Cited by 106 publications

References 21 publications

RETRACTED: Fabrication and mechanical characterization of a polyvinyl alcohol sponge for tissue engineering applications

RETRACTED: Fabrication and mechanical characterization of a polyvinyl alcohol sponge for tissue engineering applications

Evidence against proteoglycan mediated collagen fibril load transmission and dynamic viscoelasticity in tendon

Congruence of Imaging Estimators and Mechanical Measurements of Viscoelastic Properties of Soft Tissues

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