The effects of several pre-and postharvest factors on apple cv. Braeburn browning disorder (BBD) incidence using a nine-factor experimental design has been investigated. The design allowed the determination of the effects of single factors as well as their interaction with growing season and storage time. BBD increased in severity with storage duration. BBD incidence was reduced with calcium and potassium fertilizers application, while it was increased when triazoles were used. Delayed controlled atmosphere (DCA) application resulted in less BBD in storage, while treatment with 1-methylcyclopropene (1-MCP) increased BBD incidence. More BBD was observed in fruit stored at above optimal CO 2 levels. BBD incidence was increased when O 2 concentration in CA was increased from 1 kPa to 3 kPa (optimum CA) or 6 kPa. Finally, the various factors showed a different effect for different growing seasons and storage time. These findings suggest a possible mechanism for the development of BBD. Further work should focus on extending the experimental design to include the interactions between the different pre-and postharvest factors.Keywords: Braeburn browning disorder; fertilizers; triazoles; controlled atmosphere; 1-methylcyclopropene Malus domestica Borkh., cv. Braeburn is a popular apple cultivar worldwide. To facilitate year-round availability of fruit, apples are stored at low temperature under controlled atmosphere (CA) conditions. Under the commercial storage conditions, apples can be stored well as a result of their reduced metabolic rate. The storability of cv. Braeburn is, however, limited by the development of internal browning (Elgar et al. 1999). Affected fruit show patches of brown tissue which can result in cavity formation (Elgar et al. 1998). The combination of brown flesh and off flavours makes brown apples unacceptable in the market, resulting in economic losses.Different apple varieties vary in their susceptibility to browning (Streif 2008). Cv. Braeburn has a high skin resistance (Rajapakse et al. 1990) turning the skin into a stronger diffusion barrier as compared to some other apple cultivars. Together with a dense cellular organization this results in relative high internal CO 2 concentration (Herremans et