Stochastic Modelling of Solution Particle Movement: An Individual Case of Coupled Concentration Gradient Dependent and Independent Movements of Efavirenz

Abstract

This work proposed a coupled model of diffusion. It adopted two forms of coupled movement, the interacting and non-interacting driven forms of movement of a solution particle of efavirenz concentration measured in blood plasma. Data from projected pharmacokinetics in a patient on efavirenz were used. A relationship between interacting and non-interacting diffusion was suggested through a stochastic differential equation. The solution particle with a small value of relative acceleration drift to its active neighbourhood was projected to have a corresponding high transport/interacting diffusion.