Abstract:Stir bar sorptive extraction-liquid desorption (SBSE-LD) has been applied as an efficient sample preparation method for the analysis of beer bitter acids. Extracts free of almost all interfering compounds were obtained, allowing simultaneous analysis of iso-alpha-acids and reduced iso-alpha-acids. A robust micellar electrokinetic chromatography (MEKC) method was developed that enables fast separation of iso-alpha-acids and reduced iso-alpha-acids. Quantitative data are in good agreement with results obtained b… Show more
“…As an alternative to TD, the analyst can use LD. Sampling can also be performed in the headspace of a liquid or a solid sample, the so-called head space sorptive extraction (HSSE) method [45][46][47][48][49][50][51][52], and LD is used [18][19][20][21][22][23][24][25][26][27][28][29][53][54][55]. Approximately 100-200 l of an organic solvent, such as methanol and acetonitrile, is used for the desorption.…”
Section: Stir Bar Sorptive Extractionmentioning
confidence: 99%
“…The desorption time is approximately 5-10 min. In the case of LD, the sample is subjected to conventional HPLC [18][19][20][21][22][23][24][25][26][27][28], CE [28,29] or GC with large-volume injection (LVI) [53][54][55].…”
Section: Stir Bar Sorptive Extractionmentioning
confidence: 99%
“…The former process has high sensitivity because the entire extract can be analyzed by TD and GC. On the other hand, the latter process can be applied to high performance liquid chromatography (HPLC) [18][19][20][21][22][23][24][25][26][27][28] or capillary electrophoresis (CE) [28,29], and high polarity or thermally labile compounds can be analyzed.…”
“…As an alternative to TD, the analyst can use LD. Sampling can also be performed in the headspace of a liquid or a solid sample, the so-called head space sorptive extraction (HSSE) method [45][46][47][48][49][50][51][52], and LD is used [18][19][20][21][22][23][24][25][26][27][28][29][53][54][55]. Approximately 100-200 l of an organic solvent, such as methanol and acetonitrile, is used for the desorption.…”
Section: Stir Bar Sorptive Extractionmentioning
confidence: 99%
“…The desorption time is approximately 5-10 min. In the case of LD, the sample is subjected to conventional HPLC [18][19][20][21][22][23][24][25][26][27][28], CE [28,29] or GC with large-volume injection (LVI) [53][54][55].…”
Section: Stir Bar Sorptive Extractionmentioning
confidence: 99%
“…The former process has high sensitivity because the entire extract can be analyzed by TD and GC. On the other hand, the latter process can be applied to high performance liquid chromatography (HPLC) [18][19][20][21][22][23][24][25][26][27][28] or capillary electrophoresis (CE) [28,29], and high polarity or thermally labile compounds can be analyzed.…”
“…Beer, wine, and spirits were subject to MEKC analysis [71,107,126,166,167]. These and other beverages were analyzed for amino acids [126,166], phenols [71,166], hop acid [107], carbohydrates [167], and even vitamin content [166,168].…”
This review contains nearly 200 reference citations, and covers advances in electrokinetic capillary chromatography based on micelles, including stabilized micelle complexes, polymeric and mixed micelles from 2003-2004. Detection strategies, analyte determinations, and applications in micellar electrokinetic capillary chromatography (MEKC) are discussed. Information regarding methods of analyte concentration, analyte specific analyses, and nonstandard micelles has been summarized in tabular form to provide a means of rapid access to information pertinent to the reader.
“…Recently, the application of a new solventless extraction method named stir bar sorptive extraction (SBSE) has been described [15]. SBSE combined with liquid desorption (LD) was successfully applied for the analysis of bitter compounds in beer and wort by LC [16], and in beer by micellar electrokinetic chromatography (MEKC) [17].…”
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