Stimulated in vitro bone-like apatite formation by a novel laser processing technique

Calcium orthophosphate deposits: Preparation, properties and biomedical applications

“…The authors revealed that ion-substituted CDHA was rapidly deposited from SBF onto the irradiated area of inorganic substrates, while no deposition occurred onto the surface of non-irradiated area of the same substrates. This occurred due to formation of small CaPO 4 crystals during irradiation, which further facilitated the growth of thicker deposits on the irradiated area of the substrates [632]. Similar results were also obtained for both polymeric [633,634] and HA [635] …”

Liquid‐phase laser process for simple and area‐specific calcium phosphate coating

“…Since the late 2000s, liquid-phase laser processes, that is, laser irradiation onto a solid substrate or powder in a liquid medium, have attracted attention as a novel approach for material production. [22][23][24][25] Recently, Pecheva et al 24 developed a CaP coating technique for a metal substrate using a liquid-phase laser process with a high-energy laser (on the order of 1 kW/mm 2 ) followed by aging in a supersaturated CaP solution. More recently, we applied this coating technique to a polymer substrate using a weaker pulsed laser (on the order of 10 mW/mm 2 ).…”

Physicochemical fabrication of calcium phosphate-based thin layers and nanospheres using laser processing in solutions

“…25,[45][46][47] A critical disadvantage of conventional biomimetic processes is their impracticality; they are usually time-consuming (hours to days) due to the multiple steps, including a complicated surfacemodification step, and the relatively low growth rate of CaP. To overcome this disadvantage, physical stimulation (e.g., laser irradiation, [50][51][52][53][54] ultraviolet (UV) irradiation, 55,56 and microwave irradiation [57][58][59][60] ) has been introduced into biomimetic processes. In this review, we focus on the laser irradiation, specifically, laser processing in a supersaturated CaP solution.…”

“…Laser stimulation was initially applied as a CaP-precoating method before the immersion step in supersaturated CaP solution. [50][51][52][53][54] Such two-step CaP coating techniques are described in Section 2.2. Recently, these twostep techniques have been refined, and one-step CaP coating was achieved using a laser-assisted biomimetic (LAB) process; [38][39][40][41][42] this process is described in detail in Section 2.3.…”