Sterile keratitis after corneal collagen crosslinking in a child

Arora, Ritu; Jain, Parul; Gupta, Deepa; Goyal, Jawahar Lal

doi:10.1016/j.clae.2012.06.002

Cited by 36 publications

(29 citation statements)

References 12 publications

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“…The standard CXL, Dresda protocol, 1 was followed in all of the studies. [12][13][14][15][16][17][18][19][20][21] The average size of epithelial debridement was 7.66 ± 0.87 mm. The most common postoperative antibiotical treatment was fluoroquinolones.…”

Section: Resultsmentioning

confidence: 99%

“…12 This group has a low virulence and belongs to common commensals of the oral cavity, gastrointestinal and female genitourinary tracts. In this case, the patient admitted to cleaning the bandage contact lens in his mouth before reapplying it into his treated eye, and the break in the epithelium allowed these microbes to invade and infect his cornea.…”

Section: Discussionmentioning

confidence: 99%

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Infectious Keratitis Following Corneal Crosslinking: A Systematic Review of Reported Cases: Management, Visual Outcome, and Treatment Proposed

Abbouda

Abicca

Alió

2014

Seminars in Ophthalmology

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Only 10 cases of infectious keratitis following corneal crosslinking are published. The most virulent pathogens were Pseudomonas aeruginosa and Acanthamoeba. Less virulent organisms were Escherichia coli and S. epidermidis. Two cases of herpes keratitis were described, suggesting the possibility of systemic antiviral prophylaxis before corneal crosslinking treatment. The most common risk factor of infections identified was postoperative incorrect patient behavior.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Infectious Keratitis Following Corneal Crosslinking: A Systematic Review of Reported Cases: Management, Visual Outcome, and Treatment Proposed

Abbouda

Abicca

Alió

2014

Seminars in Ophthalmology

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“…Reported adverse effects with collagen crosslinking include bacterial, fungal, acanthamoeba, and sterile kerati-tis 69–75. Kymionis et al reported significant endothelial cell loss after crosslinking in thin corneas 76.…”

Section: Managementmentioning

confidence: 99%

Keratoconus: current perspectives

Vazirani

Basu²

2013

OPTH

106

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Keratoconus is characterized by progressive corneal protrusion and thinning, leading to irregular astigmatism and impairment in visual function. The etiology and pathogenesis of the condition are not fully understood. However, significant strides have been made in early clinical detection of the disease, as well as towards providing optimal optical and surgical correction for improving the quality of vision in affected patients. The past two decades, in particular, have seen exciting new developments promising to alter the natural history of keratoconus in a favorable way for the first time. This comprehensive review focuses on analyzing the role of advanced imaging techniques in the diagnosis and treatment of keratoconus and evaluating the evidence supporting or refuting the efficacy of therapeutic advances for keratoconus, such as newer contact lens designs, collagen crosslinking, deep anterior lamellar keratoplasty, intracorneal ring segments, photorefractive keratectomy, and phakic intraocular lenses.

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“…Severe dry eye is a further contraindication as it may hinder re‐epithelialisation and thereby increase the risk of post‐surgery infection; such conditions should be managed with punctual plugging and lubricants before considering CXL . This is also true of patients with conjunctival vernal disease, where cases of sterile keratitis have been reported . In such eyes, pre‐operative management with topical steroids and even systemic immune‐suppressives should be instigated to ensure any conjunctival atopic disease is in full remission before considering CXL.…”

Section: Patient Selection For CXLmentioning

confidence: 99%

“…There have been several case studies reporting the development of keratitis . Another case report described sterile keratitis as a result of pre‐existing vernal keratoconjunctivitis, emphasising the importance of careful selection of patients with other pre‐existing conditions, whether these are being treated or not. Corneal melting has also been reported, often associated with infections .…”

Section: Side Effectsmentioning

confidence: 99%

Corneal cross‐linking – a review

Meek

Hayes

2013

Ophthalmic Physiologic Optic

112

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Purpose: To review cross-linking the cornea using riboflavin and ultraviolet A light, which has been widely adopted, refined and applied in a range of corneal surgeries and pathologies where the strength of the cornea might be compromised. Recent findings: A large number of clinical trials have been carried out, most of which have demonstrated that standard cross-linking is a successful method to halt the progression of keratoconus or even aid regression. Summary: This review describes our current understanding of the technique, focussing on how cross-linking works, how the treatment is being optimised, the clinical results that have been reported to date and the potential use of the therapy in the treatment of other corneal disorders.

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Sterile keratitis after corneal collagen crosslinking in a child

Cited by 36 publications

References 12 publications

Infectious Keratitis Following Corneal Crosslinking: A Systematic Review of Reported Cases: Management, Visual Outcome, and Treatment Proposed

Infectious Keratitis Following Corneal Crosslinking: A Systematic Review of Reported Cases: Management, Visual Outcome, and Treatment Proposed

Keratoconus: current perspectives

Corneal cross‐linking – a review

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