Most cases are idiopathic (pars planitis); only few children presented associated systemic disease. Macular edema and severe vitritis at presentation are associated with increased risk of visual impairment. Cystoid macular edema is the main cause of visual impairment.

We assess repeatability of automatic measurements of a new anterior segment optical coherence tomographer and biometer (ANTERION) and their agreement with those provided by an anterior segment-optical coherence tomography device combined with Placido-disk corneal topography (MS-39) and a validated optical biometer (IOLMaster 500). A consecutive series of patients underwent three measurements with ANTERION and one with MS-39. A subgroup of patients underwent biometry also with IOLMaster 500. Repeatability was assessed by means of within-subject standard deviation, coefficient of variation (COV), and intraclass correlation coefficient (ICC). Agreement was investigated with the 95% limits of agreement. Paired t-test and Wilcoxon matched-pairs test were performed to compare the measurements of the different devices. Repeatability of ANTERION measurements was high, with ICC > 0.98 for all parameters except astigmatism (0.963); all parameters apart from those related to astigmatism revealed a COV < 1%. Repeatability of astigmatism improved when only eyes whose keratometric astigmatism was higher than 1.0 D were investigated. Most measurements by ANTERION and MS-39 showed good agreement. No significant differences were found between measurements by ANTERION and IOLMaster, but for corneal diameter. ANTERION revealed high repeatability of automatic measurements and good agreement with both MS-39 and IOLMaster for most parameters.

CMV-associated anterior uveitis has a fairly good long-term visual prognosis. Antiviral therapy can reduce the frequency of relapses, but cataracts and a chronic raise in IOP are frequent complications often requiring a surgical approach.

corneal tomography is an important tool to identify and follow up eyes with keratoconus. our study evaluate the repeatability of the automatic measurements provided in keratoconic eyes by a new anterior-segment optical coherence tomographer (AS-oct) combined with placido-disk topography (MS-39, CSO) and assess their agreement with the corresponding measurements taken with a rotating Scheimpflug camera combined with Placido-disk topography (Sirius, CSO). Mean simulated keratometry, posterior and total corneal power, total corneal astigmatism, corneal asphericity, thinnest corneal thickness, epithelial thickness, corneal diameter, and aqueous depth were evaluated. Repeatability was assessed using test-retest variability, the coefficient of variation, and the intraclass correlation coefficient; agreement was assessed by the 95% limits of agreement. Good repeatability was achieved for most parameters. Moderate repeatability was found for total corneal astigmatism measurements. the repeatability of mean simulated keratometry and total corneal power measurements worsened with more severe stages of keratoconus with a statistically significant relationship between the individual coefficient of variation and corneal power values. Agreement with the Scheimpflug camera was moderate for aqueous depth and thinnest corneal thickness and poor for most other measured parameters. the good repeatability of automatic measurements suggests the new AS-oct device to be a viable option in clinical practice of eyes with keratoconus. Keratoconus is a non-inflammatory ectasic disease characterized by progressive thinning and steepening and an apical cone-shaped protrusion of the cornea 1,2. The introduction of corneal topography first and corneal tomography later enabled researchers to develop several methods to identify keratoconic eyes 3-7. Accurate corneal imaging is now highly desirable to diagnose keratoconus, especially in its earlier stages, when visual acuity is still good. Modern anterior segment imaging techniques, such as Scheimpflug photography and optical coherence tomography (OCT), have significantly improved our ability to identify eyes with keratoconus, as they also provide pachymetric data and posterior corneal curvature measurements. Although anterior corneal surface parameters may be sufficient to discriminate between normal eyes and eyes with clinical keratoconus, using the data from both corneal surfaces as well as corneal thickness increases precision, sensitivity, specificity, and accuracy, thus significantly improving the ability to differentiate between normal eyes and subclinical keratoconus suspect eyes 7. One of the main limitations of Scheimpflug imaging is the low resolution and relatively poor quality of anterior segment scans. In this regard, anterior segment OCT (AS-OCT) is known to produce better images with higher definition. The higher resolution has made it possible, for example, to measure the corneal epithelial thickness 8-10. A parameter that has never been evaluated by Scheimpflug cameras. The purp...