Sterile Insects to Enhance Agricultural Development: The Case of Sustainable Tsetse Eradication on Unguja Island, Zanzibar, Using an Area-Wide Integrated Pest Management Approach

Vreysen, Marc J. B.; Saleh, Khalfan M.; Mramba, Furaha; Parker, Andrew G.; Feldmann, U.; Dyck, V. A.; Msangi, A. R.; Bouyer, Jérémy

doi:10.1371/journal.pntd.0002857

Cited by 57 publications

(47 citation statements)

References 6 publications

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“…A sustained SIT programme results in an increasing ratio of released sterile males to wild males (as the population decreases) eventually leading to population elimination. Major interventions over the past 50 years using SIT against agricultural pests have proved very successful, including the eradication of the New World screwworm, Cochliomyia hominivorax , from North and Central America, and the eradication of Glossina austeni tsetse flies from Unguja Island, Zanzibar [122]. The use of SIT for mosquitoes that transmit human disease has been limited due to the reduced performance of sterilized males caused by sterilization.…”

Section: Releasing Mosquitoes For Disease Controlmentioning

confidence: 99%

Biological Control of Mosquito Vectors: Past, Present, and Future

Benelli

Jeffries

Walker

2016

Insects

327

216

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Mosquitoes represent the major arthropod vectors of human disease worldwide transmitting malaria, lymphatic filariasis, and arboviruses such as dengue virus and Zika virus. Unfortunately, no treatment (in the form of vaccines or drugs) is available for most of these diseases and vector control is still the main form of prevention. The limitations of traditional insecticide-based strategies, particularly the development of insecticide resistance, have resulted in significant efforts to develop alternative eco-friendly methods. Biocontrol strategies aim to be sustainable and target a range of different mosquito species to reduce the current reliance on insecticide-based mosquito control. In this review, we outline non-insecticide based strategies that have been implemented or are currently being tested. We also highlight the use of mosquito behavioural knowledge that can be exploited for control strategies.

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Section: Releasing Mosquitoes For Disease Controlmentioning

confidence: 99%

Biological Control of Mosquito Vectors: Past, Present, and Future

Benelli

Jeffries

Walker

2016

Insects

327

216

View full text Add to dashboard Cite

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“…In this context, anti-disease strategies against African trypanosomiasis, in the broadest sense, may include: a) prevention of infection by breaking trypanosome transmission through avoiding contact with vectors by using odour-baited traps and screens to remove vectors from the vicinity of the host, 75 deploying synthetic or natural animal-derived vector repellents on the host 76,77 and/or elimination of vectors in the environment by aerial insecticide sprays [78][79][80][81] and integrated vector control using sterile insect technique; 82,83 97 considered, in a review, that anti-disease strategies could be targeted at treatments which did not eliminate the trypanosomes, but prevented the invasion of the brain by maintenance of blood brain barrier, neutralized the toxic products of trypanosomes, modulated the immune processes towards regulation of inflammation, reduction of effect of tumour necrosis factor, amplification of TGF-beta 1 and prevention of apoptosis of lymphocytes. Therefore, the anti-disease strategies propose to promote disease tolerance which is an ability of the host to limit the health consequences of the infective pathogen in spite of burden of infection.…”

Section: Anti-disease Strategies Against Trypanosomiasismentioning

confidence: 99%

Evolving anti-disease strategies from biochemical pathogenesis of african trypanosomiasis

Igbokwe¹

2018

ACP

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African trypanosomes are transmitted biologically by tsetse flies (Glossina spp) to humans and animals to cause African trypanosomiasis or trypanosomosis (sleeping sickness or Ngana). The pathology associated with the disease includes blood dyscrasia (anemia, leucopenia, thrombocytopenia), organ damage and inflammation. The infected host's metabolism is altered in response to the disease. The biochemical configuration and functions of the cell membrane, mitochondria, and cytosolic components are deranged by the infection. Cells of the infected host respond biochemically by producing chemical signals which regulate biochemical pathways, influence inflammatory responses and modify structural components. Several biochemical tools have been used to elucidate the biomolecules expressed in the disease. These biomolecules are also markers for diagnostic purposes and pathophysiological evaluations. The technologies involved in the biochemical studies are expanding from basic techniques of colorimetry, spectophotometry, and chromatography to sophisticated mass spectrometry. There are new trends employing systematics such as genomics, proteomics and metabolomics (metabonomics). The goal is to identify molecules and biochemical loci which can provide avenue for anti-disease strategies needed to treat and control the disease.

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“…This technology is based on the mass-rearing production of male mosquitos sterilised under X-rays or by irradiation (Gamma). This technology is very well applied on agricultural pests and other vector species like the tsetse fly (Dicko et al, 2014;Vreysen et al, 2014), and can be very powerful on insect population suppression or even eradication. However, successful population suppression for Ae.…”

Section: Genetic Controlmentioning

confidence: 99%

Abbreviations and acronyms

2018

Safety Assessment of Transgenic Organisms in the Environment, Volume 8

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This work is published under the responsibility of the Secretary-General of the OECD. The opinions expressed and arguments employed herein do not necessarily reflect the official views of OECD member countries.This document, as well as any data and any map included herein, are without prejudice to the status of or sovereignty over any territory, to the delimitation of international frontiers and boundaries and to the name of any territory, city or area.Please cite this publication as: OECD (2018) The statistical data for Israel are supplied by and under the responsibility of the relevant Israeli authorities. The use of such data by the OECD is without prejudice to the status of the Golan Heights, East Jerusalem and Israeli settlements in the West Bank under the terms of international law.Photo credits: Cover © Maks Ershov.Corrigenda to OECD publications may be found on line at: www.oecd.org/about/publishing/corrigenda.htm. © OECD 2018You can copy, download or print OECD content for your own use, and you can include excerpts from OECD publications, databases and multimedia products in your own documents, presentations, blogs, websites and teaching materials, provided that suitable acknowledgment of the source and copyright owner(s) is given. All requests for public or commercial use and translation rights should be submitted to rights@oecd.org. Requests for permission to photocopy portions of this material for public or commercial use shall be addressed directly to the Copyright Clearance Center (CCC) at info@copyright.com or the Centre francais d'exploitation du droit de copie (CFC) at contact@cfcopies.com. FOREWORD │ 3SAFETY ASSESSMENTOF TRANSGENIC ORGANISMSIN THE ENVIRONMENT, VOLUME 8 © OECD 2018 ForewordModern biotechnologies are applied to plants species (crops, flowers, trees), animals and micro-organisms. The safety of the resulting transgenic organisms when released in the environment for their use in agriculture, forestry, the food and feed industry or for other applications represents a challenging issue. Genetically engineered products are rigorously assessed by their developers during their elaboration, and by governments when ready for release, to ensure high safety standards. This remains essential with new biotechnology developments using insects to fight against disease outbreaks: engineered mosquitoes need to be evaluated through a scientifically sound approach to risk/safety assessment that will inform biosafety regulators and support the decision concerning the release of these novel organisms in the environment.The OECD offers a long-standing recognised expertise in biosafety and contributes to facilitating an harmonised approach. The OECD's Working Group on Harmonisation of Regulatory Oversight in Biotechnology (WG-HROB) was established in 1995. The WG-HROB gathers national authorities responsible for the environmental risk/safety assessment of products of modern biotechnology in OECD countries and other economies. International organisations and experts involved in biosafety activities are a...

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Sterile Insects to Enhance Agricultural Development: The Case of Sustainable Tsetse Eradication on Unguja Island, Zanzibar, Using an Area-Wide Integrated Pest Management Approach

Cited by 57 publications

References 6 publications

Biological Control of Mosquito Vectors: Past, Present, and Future

Biological Control of Mosquito Vectors: Past, Present, and Future

Evolving anti-disease strategies from biochemical pathogenesis of african trypanosomiasis

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