Stereotactic Core-Needle Breast Biopsy: A Multi-institutional Prospective Trial

Brenner, R. James; Bassett, Lawrence W.; Fajardo, Laurie L.; Dershaw, D. David; Evans, W. P.; Hunt, R. Thomas N.; Lee, Chi K.; Tocino, Irena; Fisher, Paul R.; McCombs, Marie M.; Jackson, Valerie P.; Feig, Stephen A.; Mendelson, Ellen B.; Margolin, Frederick R.; Bird, Richard E.; Sayre, James W.

doi:10.1148/radiology.218.3.r01mr44866

Cited by 117 publications

(56 citation statements)

References 45 publications

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“…The high ratio of malignancies in the latter study was associated with the selection of patients from high-risk groups. Other studies have also led to similar results (Brenner et al, 2001;Ciatto et al, 2006). In our study, 71.6% of the lesions in the patients who had undergone SVC biopsies were benign, and 28.4% were malignant.…”

Section: Discussionsupporting

confidence: 66%

Stereotactic Vacuum-Assisted Core Biopsy Results for Non-Palpable Breast Lesions

Agacayak¹,

Ozturk²,

Bozdogan³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: The increase in breast cancer awareness and widespread use of mammographic screening has led to an increased detection of (non-palpable) breast cancers that cannot be discovered through physical examination. One of the methods used in the diagnosis of these cancers is vacuum-assisted core biopsy, which prevents a considerable number of patients from undergoing surgical procedures. The aim of this study was to present the results of stereotactic vacuum-assisted core biopsy for suspicious breast lesions. Materials and Methods: Files were retrospectively scanned and data on demographic, radiological and pathological findings were recorded for patients who underwent stereotactic vacuum-assisted core biopsy due to suspicious mammographic findings at the Interventional Radiology Centre of the Florence Nightingale Hospital between January 2010, and April 2013. Statistical analysis was carried out using Pearson's Chi-square, continuity correction, and Fisher's exact tests. Results: The mean age of the patients was 47 years (range: 36-70). Biopsies were performed due to BIRADS 3 lesions in 8 patients, BIRADS 4 lesions in 77 patients, and BIRADS 5 lesions in 3 patients. Mammography elucidated clusters of microcalcifications in 73 patients (83%) and focal lesions (asymmetrical density, distortion) in 15 patients (17%). In terms of complications, 1 patient had a hematoma, and 2 patients had ecchymoses (3/88; 3.3%). The histopathologic results revealed benign lesions in 63 patients (71.6%) and malignant lesions in 25 patients (28.4%). The mean duration of the procedure was 37 minutes (range: 18-55).Although all of the BIRADS 3 lesions were benign, 22 (28.6%) of the BIRADS 4 lesions and all of the BIRADS 5 lesions were malignant. Among the malignant cases, 80% were in situ, and 20% were invasive carcinomas. These patients underwent surgery. Conclusions: In cases where non-palpable breast lesions are considered to be suspicious in mammography scans, the vacuum-assisted core biopsy method provides an accurate histopathologic diagnosis thus preventing a significant number of patients undergoing unnecessary surgical procedures.

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Section: Discussionsupporting

confidence: 66%

Stereotactic Vacuum-Assisted Core Biopsy Results for Non-Palpable Breast Lesions

Agacayak¹,

Ozturk²,

Bozdogan³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…It has been demonstrated that SNCB has high sensitivity in the diagnosis of both malignant and benign conditions. 3,4,7,8,10 SNCB reduces the financial and personal cost of diagnosis, leads to a reduction in surgical biopsies, and increases the positive predictive value of surgical biopsy. 43,44 Morbidity is reduced, and cosmesis is better compared with surgery.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8][9][10] Previous studies have reported high rates of concordance between the histologic findings of core biopsy and surgical biopsy. An exception is atypical ductal hyperplasia (ADH), which is an unreliable core biopsy diagnosis that requires surgical biopsy, 1,8,10 -13 because low-grade ductal carcinoma in situ (DCIS) and ADH may be confused on core biopsy due to the small volume of tissue sampled.…”

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confidence: 99%

Fourteen‐gauge needle core biopsy of mammographically evident radial scars

Cawson¹,

Malara²,

Kavanagh³

et al. 2003

Cancer

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The effect of pH on the precipitation of soy protein between pH 4 and 6.8 was investigated. Precipitation between pH 5.7 and 6.8 gave a binary liquid‐liquid separation in which a protein‐rich secondary liquid phase containing between 20 – 30 wt % protein of 80 – 99% purity in glycinin formed as droplets of 1 – 10 μm. The droplets could be coalesced upon centrifugation to form a homogeneous bottom liquid layer. The high‐protein concentration phase was stable (did not precipitate or crystallize) for up to several months when stored at 4°C. Stable high‐protein liquid phases have not previously been reported. In the pH region for which liquid‐liquid separation occurred (pH 6.15 to 5.35), the droplet‐size distribution was controlled by nucleation and growth. No drop breakage, and little or no drop coalescence was observed. Mixer speed and geometry did not have a large effect on the size of the protein‐rich droplets in suspension. Nucleation occurred in two separate bursts at pH 6.15 and pH 5.85, followed by growth of the new nuclei as pH was decreased. Thus, the drop‐size distribution was monomodal between 6.15 and 5.85, and bimodal between pH 5.85 and 5.35. At pH 5.6 and below, protein precipitated as amorphous material which intertwined with and bound primary particles into aggregates. These agglomerates grew with decreasing pH, particularly below pH 5.35, as more protein precipitated with amorphous material acting as a binder. The addition of NaCl prevented the liquid‐liquid separation at higher pH. Instead solid precipitates of a different morphology were formed at low‐pH only. © 2007 American Institute of Chemical Engineers AIChE J 2007

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“…Stereotactic incisional core breast biopsy (SCBB) has been shown to be a useful method for investigating nonpalpable masses or suspicious calcifications that are detected on screening mammogram (1)(2)(3)(4)(5)(6). In many specialized centers, it has become the preferred method of tissue sampling for such lesions.…”

mentioning

confidence: 99%

Histologic and Radiographic Analysis of Ductal Carcinoma In Situ Diagnosed Using Stereotactic Incisional Core Breast Biopsy

et al. 2002

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Background: Stereotactic incisional core breast biopsy (SCBB) is a highly specific technique for diagnosing ductal carcinoma in situ (DCIS) in patients with suspicious mammographic microcalcifications. However, its sensitivity for excluding the presence of coexisting occult invasive disease in this setting is not fully established. Design: We correlated SCBB findings to subsequent lumpectomy/mastectomy (lx/mx) results in 122 cases of DCIS. In 29 of these cases, the SCBB showed microscopic invasion (n ‫؍‬ 15) or foci that were suspicious for invasion (n ‫؍‬ 14).

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Stereotactic Core-Needle Breast Biopsy: A Multi-institutional Prospective Trial

Cited by 117 publications

References 45 publications

Stereotactic Vacuum-Assisted Core Biopsy Results for Non-Palpable Breast Lesions

Stereotactic Vacuum-Assisted Core Biopsy Results for Non-Palpable Breast Lesions

Fourteen‐gauge needle core biopsy of mammographically evident radial scars

Histologic and Radiographic Analysis of Ductal Carcinoma In Situ Diagnosed Using Stereotactic Incisional Core Breast Biopsy

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