Stereotactic breast brachytherapy applied peripherally using a compression applicator and HDR Ir-192

Rivard, Mark J.; Bricault, Raymond J.; Melhus, Christopher S.; Hiatt, Jessica R.; Sioshansi, P.; Wazer, David E.

doi:10.1016/j.brachy.2007.02.012

Cited by 4 publications

(4 citation statements)

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“…The MCNP5 code has been previously used in brachytherapy dosimetry (Rivard et al 2007, Polgar and Major 2009, Yang and Rivard 2008, Yang et al 2011. In this study, MCNP5 Monte Carlo code (X-5 Monte Carlo Team) was used to simulate the treatment devices such as custom-designed applicators, tissue equivalent phantom and other accessories, which were needed for designed an under compression irradiation technique.…”

Section: Monte Carlo Simulation By Mcnp5 Codementioning

confidence: 99%

“…AccuBoost ® (Advanced Radiation Therapy LLC, Bil-lerica, MA) is a non-invasive brachytherapy technique and a sample of under compression treatment technique in which a boost radiation dose is delivered to the breast cancer patient by compressing the breast tissue in order to minimize the dose to the healthy tissue. In this system, the breast is immobilized via a moderate compression, followed by a 2D mammographic imaging for target localization (Rivard et al 2007, Hoover et al 2011. Figure 1 illustrates the schematic diagram of the breast treatment with the AccuBoost application system.…”

Section: Introductionmentioning

confidence: 99%

“…However, they did not investigate the deformation effect of breast during irradiation sessions (Wooten et al 2010). Rivard et al (2007Rivard et al ( , 2009 and Yang et al (2008Yang et al ( , 2009Yang et al ( , 2010 investigated the dose distribution of different AccuBoost ® applicators in various non-deformable phantoms with Monte Carlo simulation (MCNP5), ionization chambers, and EBT GafChromic ™ film. Also, Sioshani et al (Polgar and Major 2009) used the patient's CT images that were obtained with the breast compressed to generate 3D dose distributions only in the compressed breast.…”

Section: Introductionmentioning

confidence: 99%

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Calculation of dose distribution in compressible breast tissues using finite element modeling, Monte Carlo simulation and thermoluminescence dosimeters

et al. 2015

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Compression is a technique to immobilize the target or improve the dose distribution within the treatment volume during different irradiation techniques such as AccuBoost(®) brachytherapy. However, there is no systematic method for determination of dose distribution for uncompressed tissue after irradiation under compression. In this study, the mechanical behavior of breast tissue between compressed and uncompressed states was investigated. With that, a novel method was developed to determine the dose distribution in uncompressed tissue after irradiation of compressed breast tissue. Dosimetry was performed using two different methods, namely, Monte Carlo simulations using the MCNP5 code and measurements using thermoluminescent dosimeters (TLD). The displacement of the breast elements was simulated using a finite element model and calculated using ABAQUS software. From these results, the 3D dose distribution in uncompressed tissue was determined. The geometry of the model was constructed from magnetic resonance images of six different women volunteers. The mechanical properties were modeled by using the Mooney-Rivlin hyperelastic material model. Experimental dosimetry was performed by placing the TLD chips into the polyvinyl alcohol breast equivalent phantom. The results determined that the nodal displacements, due to the gravitational force and the 60 Newton compression forces (with 43% contraction in the loading direction and 37% expansion in the orthogonal direction) were determined. Finally, a comparison of the experimental data and the simulated data showed agreement within 11.5% ± 5.9%.

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Section: Monte Carlo Simulation By Mcnp5 Codementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Calculation of dose distribution in compressible breast tissues using finite element modeling, Monte Carlo simulation and thermoluminescence dosimeters

et al. 2015

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“…The AccuBoost system employs a conventional mammography unit, a computed radiography ͑CR͒ system, and a high dose rate ͑HDR͒ 192 Ir brachytherapy source remote afterloading system to deliver breast brachytherapy in a peripheral, noninvasive manner. [1][2][3][4][5] The breast is compressed in the mammography unit, and a radio-opaque graticule is positioned over the treatment area using the CR system. Once the graticule is properly positioned, the graticule is swapped with the treatment applicator for brachytherapy delivery where the graticule center and the geometric center of the applicator are aligned.…”

Section: Introductionmentioning

confidence: 99%

Monte Carlo simulations and radiation dosimetry measurements of peripherally applied HDR breast brachytherapy D‐shaped applicators

Yang

Rivard

2009

Medical Physics

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Conformal dose coverage for accelerated partial breast irradiation or radiotherapy boost can be obtained with AccuBoost® D-shaped brachytherapy applicators using a flattened surface positioned near the patient. Three D-shaped applicators (D45/D53/D60) were dosimetrically characterized using Monte Carlo methods (MCNP5), air ionization chambers (Farmer and Markus), and radiochromic film (GafChromic EBT) in polystyrene and ICRU 44 breast tissue. HDR 192Ir source dwell times were either constant or optimized to improve skin dose uniformity. Scatter dose decreased as depth decreased. 10 mm beyond the applicator aperture, dose reductions of 90% and 51% were observed at depths of 0 and 30 mm, respectively. Similarly, planar dose uniformity improved as depth decreased and was also due to scatter and applicator geometry. Dose uniformity inside the applicator aperture was approximately 11% and 15% for all three applicators at the skin and 30 mm deep, respectively. Depth dose measurements in polystyrene using ion chamber and radiochromic film agreed with Monte Carlo results within 2%. Discrepancies between film and Monte Carlo dose profiles at 30 mm depth were within 1%.

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Emerging Technologies Part II: Novel Sources and Delivery Systems

Hepel¹,

Sioshansi²,

Rivard³

et al. 2009

Accelerated Partial Breast Irradiation

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Stereotactic breast brachytherapy applied peripherally using a compression applicator and HDR Ir-192

Cited by 4 publications

References 0 publications

Calculation of dose distribution in compressible breast tissues using finite element modeling, Monte Carlo simulation and thermoluminescence dosimeters

Calculation of dose distribution in compressible breast tissues using finite element modeling, Monte Carlo simulation and thermoluminescence dosimeters

Monte Carlo simulations and radiation dosimetry measurements of peripherally applied HDR breast brachytherapy D‐shaped applicators

Emerging Technologies Part II: Novel Sources and Delivery Systems

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