Abstract:The physical binding of m-electron models of different benz [a]anthracene metabolites to DNA exhibits widely varying properties. In this study, the binding properties of two nonreactive m-electron models of reactive metabolites of benz[a]anthracene were examined. The models investigated are 1,2,3,4-tetrahydrobenz[a]anthracene and 8,9,10,Il-tetrahydrobenz[n]anthracene. Physical binding has been studied by measuring the effects of native DNA, denatured DNA, and DNA components upon the fluorescence intensities an… Show more
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