The mechanism of particle removal in megasonic cleaning needs to be clarified so that it can be controlled and used to clean nanodevices without causing pattern damage. Single bubble behavior in a standing megasonic wave was analyzed using a compressible locally homogeneous model of a gas-liquid two-phase medium. This simulation is the first step toward understanding the particle removal mechanism in megasonic cleaning. We confirmed that our numerical method simulated the characteristics of bubble translational motion in a standing wave, in which the direction of the movement due to the primary Bjerknes force changed at the resonant radius. When the initial position of the bubble was near a moving wall, even a bubble with a radius smaller than the resonant radius moved toward the pressure node. In the three-dimensional calculations, bubble collapse near a side wall induced a higher pressure on the side wall than the maximum pressure of the megasonic wave. The bubble dynamics calculation with gas diffusion indicated that the effect of the rectified diffusion was small because the effect of the dynamic bubble motion was dominant on a timescale of several milliseconds.Semiconductor cleaning is important because contaminant particles adhering to a wafer surface reduce the quality of the semiconductor device. As the size of semiconductor devices decreases, the size of contaminant particles that can cause fatal defects also decreases. Therefore, better cleaning techniques are required. Furthermore, unconventional materials are increasingly being used to reduce power consumption and improve the speed of semiconductor devices. Conventional RCA chemical cleaning can dissolve these new materials and damage the pattern. Physical techniques for semiconductor cleaning include a cryogenic high-speed spray of micro-solid nitrogen, 1-4 an Ar aerosol method, 5 a CO 2 gas cluster method, 6 and wet laser shockwave cleaning. 7 Megasonic cleaning is a physical cleaning technique where particles are removed by the collapse of cavitation bubbles, acoustic streaming, and the surrounding pressure gradient. 8,9 However, the physical forces resulting from the collapse of cavitation bubbles can cause pattern damage. Thus, control of cavitation bubbles in the megasonic field is essential for removing contaminant particles without pattern damage during the megasonic cleaning of nanodevices.There are many experimental studies of megasonic cleaning, such as analyses of particle removal and pattern damage in deionized water with several dissolved gases 10 and observation of bubble behavior. 11 However, it is difficult to determine the mechanism of particle removal experimentally because it occurs on very small temporal and spatial scales. Therefore, theoretical and numerical studies have also been performed. Deymier et al. calculated the acoustic pressure field around the pattern on a silicon wafer and the shear stress acting on the wafer. 12 Their results suggest that the calculated shear stress is far lower than the shear strength of the silic...