Status of Triple Antigen Test among Community Acquired Febrile Illness Patient attended at Tertiary Care Hospital, Bogura

Abstract

Background: Bacterial etiologies of febrile illnesses have significantly become important due to high mortality and morbidity.
 Objective: This study aimed to identify the prevalence of rickettsial fever, brucellosis, and typhoid fever by triple antigen test.
 Methodology: This cross-sectional study was conducted at TMSS Medical College Bogura district in Bangladesh for 6 months. Febrile patients aged from 1 to 65 years of both sexes were recruited from the outpatient department of this Medical College Bogura. Blood sample were taken from all patients for antibody test by microscopic plate agglutination test according to manufacturer instruction.
 Results: A total of 140 patients were enrolled and 74/140 (52.86%) patients were positive by any of three antigens, among them female were 54/74 (72.97%), most common age group was 21 to 30 years which was 22/74(29.73%), TO titre was greater than TH titre, which was 24/36 (66.66%).
 Conclusion: The study has underscored the importance of febrile antigen detection for bacterial diseases including zoonosis such as ricketial fever, brucellosis and typhoid fever in febrile patient and thus reducing diagnostic dilemma of febrile diseases. However, further diagnostic tests for diagnosis of febrile illnesses also needed. This will be helpful for febrile patients to receive the correct diagnoses and facilitation of accurate and prompt treatment.
 Bangladesh Journal of Infectious Diseases 2020;7(1):18-21