Status of Colorectal Cancer Devices: Present Scenario

Chandel, Shammy; Akhtar, Reyhan; Sarotra, Pooja; Medhi, Bikash

doi:10.1007/s12029-015-9686-3

Cited by 4 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These feelings are experienced in severe situations, leading to various degrees of abdominal discomfort and pain after the inspection. Painless colonoscopy is a newly developed technique that relieves the pain and discomfort associated with colonoscopy examination through the use of a combination of a sedative and an analgesic [1,2]. Dezocinepropofol and fentanyl-propofol are two kinds of frequently used anesthetic combinations for achieving painless colonoscopy.…”

Section: Introductionmentioning

confidence: 99%

Analgesic, anti-inflammatory and immuno-modulatory effects of dezocine-propofol anesthesia combination following colonoscopy

Li¹,

Zhuang²,

Chen³

2017

Trop. J. Pharm Res

View full text Add to dashboard Cite

Purpose: To study and compare the analgesic, anti-inflammatory and immuno-modulatory effects of dezocine-propofol, and fentanyl-propofol combinations in colonoscopy. Methods: One hundred and thirty-four patients who received painless colonoscopy in Eastern Medical -HTP), 5-hydroxy indole acetic acid (5-HIAA), substance P (SP), prostaglandin E2 (PGE2), C-reactive protein (CRP), heat shock protein 70 (HSP70), Interleukin-1 β(IL-1β), adrenocorticotropic hormone (ACTH), Cortisol (Cor), Inositol (Ins), c-peptide (C-P), immunoglobulin G (IgG) and immunoglobulin A (IgA), complement 3 (C3) and complement 4 (C4) before and during colonoscopy between the two groups of patients. However, after the examination, serum levels of SP, PGE2, CRP, HSP70, ACTH, Cor,

show abstract

Section: Introductionmentioning

confidence: 99%

Analgesic, anti-inflammatory and immuno-modulatory effects of dezocine-propofol anesthesia combination following colonoscopy

Li¹,

Zhuang²,

Chen³

2017

Trop. J. Pharm Res

View full text Add to dashboard Cite

show abstract

“…Various alternatives to the CC have been trialled with the aim of overcoming its limitations [5]. These range from modifications to the CC [6, 7] to devices which utilise alternative methods of propulsion such as an actively articulated shaft [8], an extending external sleeve [9, 10], inchworm-like motion [11], propulsion by pressurised gas [12] or passive transit through the GI tract [13].…”

mentioning

confidence: 99%

A hydraulically driven colonoscope

et al. 2016

View full text Add to dashboard Cite

BackgroundConventional colonoscopy requires a high degree of operator skill and is often painful for the patient. We present a preliminary feasibility study of an alternative approach where a self-propelled colonoscope is hydraulically driven through the colon.MethodsA hydraulic colonoscope which could be controlled manually or automatically was developed and assessed in a test bed modelled on the anatomy of the human colon. A conventional colonoscope was used by an experienced colonoscopist in the same test bed for comparison. Pressures and forces on the colon were measured during the test.ResultsThe hydraulic colonoscope was able to successfully advance through the test bed in a comparable time to the conventional colonoscope. The hydraulic colonoscope reduces measured loads on artificial mesenteries, but increases intraluminal pressure compared to the colonoscope. Both manual and automatically controlled modes were able to successfully advance the hydraulic colonoscope through the colon. However, the automatic controller mode required lower pressures than manual control, but took longer to reach the caecum.ConclusionsThe hydraulic colonoscope appears to be a viable device for further development as forces and pressures observed during use are comparable to those used in current clinical practice.

show abstract