Statistical Correlation between P�AP, Spirographs Data and Arterial and Mixed Venous Blood Gases in 22 Subjects with Chronic Obstructive Lung Disease

Timsit, Gérard; Neukirch, F; Perron, Michel; Verdier, F; Drutel, P; Legrand, Mathieu; Botto, M. J.; Lesobre, R

doi:10.1159/000398172

Cited by 3 publications

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“…The relation between the PV diameter and PAP (r = 0.62) was highly significant (p <0.001). Such a value is by less lower than the one we achieved between Pa02 and PAP (r = -0.66) which is, however, included in the range of the values mentioned in the literature (r = 0.60-0.67) [21,22], Table 5 sums up the statistical analyses aiming at assessing the capacity of esti mating the existence of pulmonary hyper tension (PAP ^2 0 mmHg) according to the échocardiographie parameters which are best correlated with PAP as to Pa02. From this table it appears that besides LPA the more sensitive échocardiographie parameter is the PV diameter.…”

Section: Resultscontrasting

confidence: 58%

Value of Two-Dimensional Echocardiography in the Identification of Pulmonary Hypertension in Chronic Obstructive Lung Disease

Mantero²,

Alpago³

et al. 1989

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Thirty-three patients suffering from chronic obstructive lung disease (COLD) were submitted to right heart two-dimensional echocardiographic (2D-ECHO) and hemodynamic study. By the subcostal approach, the right ventricle outflow tract including the pulmonary vessels was visualized in 85% of the patients. Most parameters measured on the right ventricle and pulmonary vessels were significantly higher than those recorded in the healthy control group. Very significant correlations were observed between the mean pulmonary artery pressure (PAP) and the following 2D-ECHO parameters: diameter of the pulmonary artery at valve level (r = 0.62; p < 0.001); supravalvular diameter of the pulmonary artery (r = 0.44; p < 0.03); diameter of the left branch of the pulmonary artery (r = 0.48; p < 0.05); diameter of the right branch of the pulmonary artery (r = 0.39; p < 0.05), and between the PAP and PaO₂ (r = -0.66; p < 0.001). Furthermore, the sensitivity, specificity, and accuracy of 2D-ECHO measurements were calculated to assess the presence of pulmonary hypertension. Overall sensitivity was 65%, specificity 75%, and accuracy 67%. However, by combining the value of PaO₂ with that of the pulmonary valve by means of the multiple regression analysis, sensitivity increased to 84% in identifying pulmonary hypertension. Such data demonstrate that the 2D-ECHO study of the right heart in COLD patients has to carefully measure the dimensions of the pulmonary valve and the great pulmonary vessels, as their modification are mainly linked with the presence of pulmonary hypertension. Hence, it can be concluded that 2D-ECHO if associated with PaO₂ measurement allows the physician to diagnose pulmonary hypertension in COLD with a good degree of probability.

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Section: Resultscontrasting

confidence: 58%