State-of-the-Art Technologies for Improving the Quality of Medicinal and Aromatic Plants

Roychoudhury, Aryadeep; Bhowmik, Rituparna

doi:10.1007/978-3-030-58975-2_23

Cited by 4 publications

(3 citation statements)

References 187 publications

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“…These provide a basis for further studies to ascertain clinical relevance, standardize dosage, ensure safety, and characterize deleterious off-target effects. State of the art technologies exist, such as sequencing, metabolomic and proteomic tools, to excavate undiscovered plant metabolites, improve yield and eliminate toxic compounds from valuable plant extracts [ 467 , 468 ]. Plant tissue culture techniques can eliminate the reliance on wild plants under threat [ 469 ].…”

Section: Resultsmentioning

confidence: 99%

Therapeutic roles of plants for 15 hypothesised causal bases of Alzheimer’s disease

Tyler

2022

Nat. Prod. Bioprospect.

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Alzheimer’s disease (AD) is progressive and ultimately fatal, with current drugs failing to reverse and cure it. This study aimed to find plant species which may provide therapeutic bioactivities targeted to causal agents proposed to be driving AD. A novel toolkit methodology was employed, whereby clinical symptoms were translated into categories recognized in ethnomedicine. These categories were applied to find plant species with therapeutic effects, mined from ethnomedical surveys. Survey locations were mapped to assess how this data is at risk. Bioactivities were found of therapeutic relevance to 15 hypothesised causal bases for AD. 107 species with an ethnological report of memory improvement demonstrated therapeutic activity for all these 15 causal bases. The majority of the surveys were found to reside within biodiversity hotspots (centres of high biodiversity under threat), with loss of traditional knowledge the most common threat. Our findings suggest that the documented plants provide a large resource of AD therapeutic potential. In demonstrating bioactivities targeted to these causal bases, such plants may have the capacity to reduce or reverse AD, with promise as drug leads to target multiple AD hallmarks. However, there is a need to preserve ethnomedical knowledge, and the habitats on which this knowledge depends. Graphical Abstract

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Section: Resultsmentioning

confidence: 99%

Therapeutic roles of plants for 15 hypothesised causal bases of Alzheimer’s disease

Tyler

2022

Nat. Prod. Bioprospect.

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“…Climate change poses new challenges for agriculture. Maize crop transformation aims to develop varieties that can thrive in changing climatic conditions, ensuring food security in the face of global warming (Roychoudhury and Bhowmik, 2021).…”

Section: Adaptation To Climate Changementioning

confidence: 99%

Maize Crop Transformation With Crispr: State-of-the-Art and Future Directions

2023

Trends Biotechnol Plant Sci

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The integration of CRISPR-Cas9 technology in maize crop transformation has ushered in a new era of precision and efficiency in agriculture. This paper explores the multifaceted role of CRISPR in maize agriculture, with a focus on its potential to enhance crop resilience, productivity, and nutritional quality. The first section delves into the core principles of the CRISPR-Cas9 system, emphasizing its ability to facilitate precise genetic modifications. CRISPR technology has enabled the development of maize varieties with enhanced disease resistance, mitigating the impact of devastating pathogens like maize streak virus (MSV) and reducing the need for chemical pesticides. The second section explores how CRISPR is used to bolster drought tolerance and climate adaptation in maize. By modifying genes related to water use efficiency, root architecture and stress response, researchers have created maize varieties that withstand water-limited environments and adapt to changing climatic conditions. The third section delves into yield improvement strategies using CRISPR technology. Precision breeding optimizes plant architecture, enhances grain size and quality, and mitigates factors like lodging. These advancements offer the promise of higher maize productivity without expanding agricultural land. Moreover, the nutritional enrichment of maize through CRISPR modifications addresses public health concerns by elevating the content of essential nutrients. The paper also emphasizes the importance of responsible use, equitable access, regulatory frameworks, and ethical considerations in the future of CRISPR-enhanced maize agriculture. In closing, the role of CRISPR in maize crop transformation is a beacon of hope for the global food system. Its potential to increase food security, support sustainable agriculture, and improve public health underscores its significance in addressing the challenges of a changing world. As society navigates the future of maize agriculture, it must do so with the responsible application of CRISPR technology, ensuring that it benefits humanity as a whole.

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“…The market for medicinal plants in the European Union has experienced increased interest in terms of rapidly grown medicinal and aromatic plants (MAPs) over the past decade [2]. Approximately 80% of the world's population depends on the secondary metabolites of different medicinal and aromatic plants [3]. Romania has shown significant interest in the MAP market, demonstrated by high demand for new, valuable, quality crops.…”

Section: Introductionmentioning

confidence: 99%

Growth Characteristics of Dracocephalum moldavica L. in Relation to Density for Sustainable Cropping Technology Development

et al. 2022

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Medicinal and aromatic plants hold a high share of interest in Romania. To offset the harvesting of spontaneous flora and ensure the sustainable conservation of natural resources, the cropping of highly valuable plants of interest represents a priority for the current agricultural system. This study was conducted due to the need for more balance in species exploitation. Therefore, it assessed the emergence dynamics, leaf appearance, growth and development of the plants depending on row spacing and plant distance. The research was conducted at the INCDCSZ Brașov, within the Technology Department, Laboratory of Medicinal and Aromatic Plants. The density of planting is the most important factor. Plants sown in continuous rows showed the highest yields of fresh and dry herbs, especially when the distance between the rows was set to 25 cm. Row-by-row distances of 50 cm ensure average values for all growth and development parameters. An increase in the row-by-row distance up to 70 cm drastically reduced the dry biomass up to 7.89 t ha−1 in continuous rows, followed by a 2 and 2.5 t ha−1 decrease for 15 cm and 25 cm plant-by-plant distances, respectively. Continuous row planting and a 25 cm row-by-row distance negligibly reduce the climate impact on growth and development. Greater spaces between plants leads to an average increase in individual development, but with a decrease in the total potential yield.

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State-of-the-Art Technologies for Improving the Quality of Medicinal and Aromatic Plants

Cited by 4 publications

References 187 publications

Therapeutic roles of plants for 15 hypothesised causal bases of Alzheimer’s disease

Therapeutic roles of plants for 15 hypothesised causal bases of Alzheimer’s disease

Maize Crop Transformation With Crispr: State-of-the-Art and Future Directions

Growth Characteristics of Dracocephalum moldavica L. in Relation to Density for Sustainable Cropping Technology Development

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