Staphylococcus aureus nasal carriage among medical students

Carmona-Torre, Francisco; Torrellas, Beatriz; Rúa, Marta Covela; Yuste, José Ramón; Pozo, J.L. del

doi:10.1016/s1473-3099(17)30188-3

Cited by 19 publications

(8 citation statements)

References 3 publications

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“…None of these factors were found to play a significant role in S. aureus nasal colonization. This is in agreement with most other studies which reported no correlation between S. aureus nasal colonization and clinical exposure [29,31,33,43,47,48,54,55]. To the contrary, some studies suggested possible correlation between clinical exposure and S. aureus nasal colonization [35,44,49], while a few studies suggested strong correlation [56,57].…”

Section: Discussionsupporting

confidence: 91%

“…Investigating the role of medical students as nasal carriers of MRSA has attained recent interest as medical students constitute an important but forgotten part of the healthcare workforce that interacts frequently with patients and are less informed and possibly not well trained about infection control measures [29]. Several previous studies have investigated the prevalence of MRSA carriers among medical students [30][31][32][33] which proved their important role in nosocomial infections [34,35].…”

Section: Introductionmentioning

confidence: 99%

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Nasal colonization by methicillin-sensitive and methicillin-resistant Staphylococcus aureus among medical students

Al‐Akchar

Himsawi

Abu-Raideh

et al. 2018

J Infect Dev Ctries

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Introduction: Nasal carriers of methicillin-resistant Staphylococcus aureus (MRSA) are common and play an important role in nosocomial infections. The prevalence rate and characterization of nasal carriers of MRSA among medical students in Jordan has not been investigated before. Methodology: The resistance of S. aureus to several antibiotics was tested using disc diffusion method, automatic Vitek 2, and penicillin binding protein (PBP) 2 slide test. Bacterial species and resistance genes were confirmed using molecular analysis of three relevant genes by real-time PCR. Two hundred ninety nasal swabs were collected from medical students at Hashemite University from June 2015 to August 2016. All participants signed a voluntary consent form and filled a predesigned questionnaire. Results: The mean age of participants was 19.7 ± 2 years and 61.7% of them were males. 63 out of the 290 (21.7%) samples were identified to have S. aureus, 56 (19.3%) were methicillin-sensitive S. aureus (MSSA) and 7 (2.4%) were MRSA. S. aureus nasal colonization significantly associates with male gender (OR = 1.7, CI = 0.94-3.18, P = 0.049) and chronic illnesses (OR = 4.0, CI = 1.52-10.65, P = 0.006). Consistency between disc diffusion, Vitek 2, and PBP 2 methods for MRSA screening were satisfactory compared to molecular analysis. All MRSA samples were positive for SCCmec:orfx junction gene (MRSA-specific), nuc gene (S. aureus- specific), mecA gene (PBP-mediated resistant), and PBP2 production. All MRSA isolates were multi-drug resistant and were sensitive to Linezolid, Vancomycin, and Tigecycline. Conclusions: This study confirms that nasal colonization by MRSA among medical students necessitates further attention to prevent nosocomial infections.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Nasal colonization by methicillin-sensitive and methicillin-resistant Staphylococcus aureus among medical students

Al‐Akchar

Himsawi

Abu-Raideh

et al. 2018

J Infect Dev Ctries

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“…However, the number of students that were colonized at some point during the four years increased considerably (72%). This value was much higher than the rates reported among medical students in other European countries, namely in France (27%) [ 20 ], Spain (35%) [ 21 ], Austria (25%) [ 22 ], and Bosnia (11%) [ 23 ] or in other continents, namely in the USA (16%) [ 24 ], Malaysia, Taiwan and Japan (10–36%) [ 25 – 27 ] and Colombia (25%) [ 28 ]. These differences may be due to the fact that the present study included a considerably higher number of screening time points (n = 14) compared to the previous studies; most were cross-sectional and therefore performed at a single screening point and the few prospective longitudinal studies usually evaluated the nasal carriage up to three time points.…”

Section: Discussioncontrasting

confidence: 55%

Carriage of Staphylococcus aureus among Portuguese nursing students: A longitudinal cohort study over four years of education

2017

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BackgroundStaphylococcus aureus is a major human pathogen that can colonize healthy people mainly in the anterior nares. The aim of the present study was to evaluate S. aureus nasal colonization over time among Portuguese nursing students, including methicillin-resistant S. aureus (MRSA).Methods and findingsIn this longitudinal cohort study, we collected 280 nasal swabs from nursing students at 14 time points over four years of schooling (2012–2016). The isolates were characterized by pulsed-field gel electrophoresis (PFGE), spa typing, multilocus sequence typing (MLST), and SCCmec typing for MRSA.Among 47 students, 20 (43%) carried methicillin-susceptible S. aureus (MSSA) at admission, but none was colonized with MRSA. A total of 19 students (40%) became colonized after exposure during the nursing training, out of which five carried MRSA. Overall, 39 students (83%) had S. aureus detected at least once during the study period. Among the 97 MSSA isolates, most (65%) belonged to four clones: PFGE A-ST30 (21%), B-ST72 (20%), C-ST508 (13%), and D-ST398 (11%). Three of the five MRSA carriers were colonized with the predominant clone circulating in Portuguese hospitals (ST22-IVh) and two with ST3162-II. Colonization of nursing students was highly dynamic with continuous appearance of strains with distinct PFGE types in the same individual.ConclusionsA considerable proportion of students became colonized by S. aureus, including MRSA, during the nursing education, evidencing this population represents an important reservoir of S. aureus. Therefore, education on infection control measures in nursing schools is of major importance.

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“…A recent study suggests that among first year medical students, knowledge on infection control measures was poor. 25 Although the medical staff of THA is kept under the vigilance of infection control practices, the medical students' adherence to the proper hygienic practices was not closely monitored and exempted from infection control programs confined to the hospital staff.…”

Section: Discussionmentioning

confidence: 99%

The relationship between the exposure to healthcare settings and colonization with methicillin-resistant Staphylococcus aureusamong medical students

Jayaweera

Pilapitiya

Kumbukgolla

2020

Germs

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Introduction Medical students who engage in clinical learning in healthcare settings can be potential methicillin-resistant Staphylococcus aureus (MRSA) carriers.Methods This is a descriptive cross-sectional study having a follow-up approach. Three batches of medical students who were studying at the Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka (1 st , 3 rd and 5 th study years of MBBS course) were screened for nasal and axillary MRSA colonization. The first-year students were screened before and 6 months after clinical learning. The knowledge of the students about infection control was scored (percentage) using a questionnaire in the one week before and later one year after the hospital exposure. Data was compared using two-sample t test.Results The percentage of MRSA colonization was 6.36% (7/110) and 49.57% (59/119) before clinical exposure and after 2.5 years of exposure, respectively (p<0.012). The percentage of correct responses obtained by the students for the questionnaire about infection control was 28% and 66.9% one week before the exposure to the hospitals and one year after the exposure to the hospitals, consecutively.Conclusions MRSA carriage was significantly associated with the time duration of the clinical training of the medical students. The knowledge of students about infection control was significantly inadequate one week before the hospital exposure and they have gained the knowledge only after being exposed to the hospitals.

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Staphylococcus aureus nasal carriage among medical students

Cited by 19 publications

References 3 publications

Nasal colonization by methicillin-sensitive and methicillin-resistant Staphylococcus aureus among medical students

Nasal colonization by methicillin-sensitive and methicillin-resistant Staphylococcus aureus among medical students

Carriage of Staphylococcus aureus among Portuguese nursing students: A longitudinal cohort study over four years of education

The relationship between the exposure to healthcare settings and colonization with methicillin-resistant Staphylococcus aureusamong medical students

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