Staphylococcus aureus nasal and pharyngeal carriage in Senegal

Abstract

Nasal and pharyngeal swabs were collected from 132 patients admitted to the Principal Hospital in Dakar (Senegal), in January and February 2012. The prevalence of Staphylococcus aureus carriage was 56.1% (n = 74): 40.2% for pharyngeal samples and 36.4% for nasal samples. None of the isolates was methicillin-resistant. Carriage was independently associated with being female (p <0.01) and large households (≥15 members) (p 0.04). The luk-PV genes encoding Panton-Valentine leukocidin (PVL) were present in 26.2% of the isolates. These data highlight the importance of the oropharynx as a site of colonization, and the high prevalence of PVL-positive isolates in Senegal as compared with industrialized countries.

Nasal Carriage of Staphylococcus aureus among Children in the Ashanti Region of Ghana

“…Children aged 2–15 years from The Gambia revealed a carriage rate of 27.3% [27]. Other carriage studies from West Africa do not allow a comparison, as either children were not included or rates were not stratified by age-groups [9,11,28]. …”

“…aureus lineages in asymptomatic carriers as well as in clinical isolates from Ghana [9,12]. Indeed, those spa -types have always been among the most frequently detected in nasal carriage studies throughout West Africa [11,28]. Spa -type t939, with a prevalence of 11% being the third most common in this study, has only been detected sporadically in other West and Central African countries, such as Angola, Gabon, Nigeria and São Tomé and Príncipe [34–37].…”

“…aureus nasal carriage [7,8]. Studies from West and Central Africa show carriage rates ranging from 21% in Ghana [9] to 29% in Gabon [10] and 36% in Senegal [11], but none of these studies focus on children.…”

Detection and antibiotic resistance pattern of Staphylococcus aureusand (MRSA) isolated from healthcare workers Nares at three Gaza hospitals, Palestine

“…However, the nasal carriage rate in this study was higher than those found in other studies that conducted in Arabic countries and other developing countries as seen in a recent publications from Libya (12.4%) [38], India (17.5%) [39], West Bank of Palestine (20.8%) [16] and Kuwait (21%) [14]. Yet, other recent studies from Saudi Arabia (76%) [10], Taiwan (67.2%) [26] This article is available from: www.iajaa.org / www.medbrary.com and Senegal (56.1%) [25] showed nasal colonization among HCWs higher than our findings. A plausible explanation for the differences in the colonization rates of S. aureus and MRSA between different countries and even some time in the same country may be due in part to differences in sample size or frequency of sampling and using different conventional and/or molecular methods among others.…”

“…First, HCWs may become infected by their own MRSA carriage strains; second, they could serve as a route of cross-transmission to patients; and finally, they may introduce the pathogen into their communities [12]. Several studies in Arabic countries and worldwide have reported that the rate of the nasal carriage of S. aureus and MRSA among HCWs ranges from 10.1%-76% [10,[12][13][14][15][16][17][18][19][20][21][22][23][24][25][26]. The screening of nasal carriage in HCWs is an important component in the control of MRSA in any health care facility [27].…”