Staphylococcus aureus infective endocarditis and septic pulmonary embolism after septic abortion

Aslam, Ahmed F.; Aslam, Ahmad Kamal; Thakur, Abhash C.; Vasavada, Balendu C.; Khan, Ijaz A.

doi:10.1016/j.ijcard.2004.11.020

Cited by 18 publications

(10 citation statements)

References 11 publications

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“…25 To date, anticoagulation therapy is not recommended for the treatment of pulmonary emboli secondary to infective endocarditis due to the increased risk of bleeding. 24 Therefore, our patient did not receive any specific treatment to prevent systemic embolism. …”

Section: Discussionmentioning

confidence: 99%

“…22,23 Effective antibiotic therapy for infective endocarditis can decrease the risk of pulmonary emboli. 24 However, in patients with infective endocarditis, the effects of prophylactic interventions to prevent systemic embolism, including pulmonary embolism, have been highly controversial. Although studies of aspirin prophylaxis demonstrated fewer embolic events, the risk of death increased under such treatment, as reported in a meta-analysis of observational studies.…”

Section: Discussionmentioning

confidence: 99%

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A massive haemothorax as an unusual complication of infective endocarditis caused byStreptococcus sanguinis

Kim

Lee

Choi

et al. 2016

Acta Clinica Belgica

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A massive haemothorax as an unusual complication of infective endocarditis caused byStreptococcus sanguinis

Kim

Lee

Choi

et al. 2016

Acta Clinica Belgica

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“…[6] With the increasing use of indwelling catheters and devices, the widespread use of hygienic syringes and increasing numbers of immunocompromised patients, cardiac SPE is now generally associated with cardiac device implants, intravascular catheters, and an immunocompromised state. [1,4,6,10,11] Occasionally, cardiac SPE can also be caused by congenital heart disease, [5,11–14] septic abortion, [15] and other conditions. In our study, the most common causes of cardiac SPE were various types of congenital heart disease, especially membranous ventricular septal defect (VSD), bicuspid aortic valve, and rupture of an aortic sinus aneurysm.…”

Section: Discussionmentioning

confidence: 99%

Cardiac septic pulmonary embolism

Song

Cao

et al. 2016

Medicine

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Based on the source of the embolus, septic pulmonary embolism (SPE) can be classified as cardiac, peripheral endogenous, or exogenous. Cardiac SPEs are the most common.We conducted a retrospective analysis of 20 patients with cardiac SPE hospitalized between 1991 and 2013 at a Chinese tertiary referral hospital.The study included 14 males and 6 females with a median age of 38.1 years. Fever (100%), cough (95%), hemoptysis (80%), pleuritic chest pain (80%), heart murmur (80%), and moist rales (75%) were common clinical manifestations. Most patients had a predisposing condition: congenital heart disease (8 patients) and an immunocompromised state (5 patients) were the most common. Staphylococcal (8 patients) and Streptococcal species (4 patients) were the most common causative pathogens. Parenchymal opacities, nodules, cavitations, and pleural effusions were the most common manifestations observed via computed tomography (CT). All patients exhibited significant abnormalities by echocardiography, including 15 patients with right-sided vegetations and 4 with double-sided vegetations. All patients received parenteral antimicrobial therapy as an initial treatment. Fourteen patients received cardiac surgery, and all survived.Among the 6 patients who did not undergo surgery, only 1 survived. Most patients in our cardiac SPE cohort had predisposing conditions. Although most exhibited typical clinical manifestations and radiography, they were nonspecific. For suspected cases of SPE, blood culture, echocardiography, and CT pulmonary angiography (CTPA) are important measures to confirm an early diagnosis. Vigorous early therapy, including appropriate antibiotic treatment and timely cardiac surgery to eradicate the infective source, is critical.

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“…Prognosis may be related to the clinical condition of the patient and the time of the diagnosis (7). Complications of SPE include pulmonary abscess, empyema, bronchopleural fistula, and pneumothorax (12). Definitive criteria for the diagnosis of SPE are difficult to suggest because histopathologic confirmation of this diagnosis has been uncommon.…”

Section: Discussionmentioning

confidence: 99%