A massive haemothorax as an unusual complication of infective endocarditis caused byStreptococcus sanguinis

Abstract

When treating infective endocarditis caused by S. sanguinis, clinicians should include haemothorax in the differential diagnosis of patients complaining of sudden chest pain.

Proteomic Approach for Extracting Cytoplasmic Proteins from Streptococcus sanguinis using Mass Spectrometry

“…Adding to the complexity of the situation is the diversity of techniques adopted by researchers for every step which impacts the sharing and comparison of results ( Perez-Riverol, Alpi, Wang, Hermjakob, & Vizcaíno, 2015 ; Vaudel et al, 2016 ). As proteomic approaches for insoluble membrane proteins have been discussed elsewhere ( Smith, 2011 ; Moore, Hess, Jorgenson, 2016 ), here we provide a proteomic approach for quantifying the soluble proteins in an oral commensal ( Siqueira & Rôças, 2017 ) and opportunistic causative agent of infective endocarditis, Streptococcus sanguinis SK36 ( Do et al, 2011 ; Kim et al, 2016 ). After sequencing the genome ( Xu et al, 2007 ) and identifying the essential genes ( Xu et al, 2011 ) of S. sanguinis SK36, the current challenge is to identify the dynamics of its proteins, especially the essential proteins, under different stress conditions that mimic clinical situations it induces, to define “pathogenesis signatures” as promising therapeutic targets.…”