Staphylococcus aureus bacteremia in patients with Hickman catheters

Dugdale, David C.; Ramsey, Paul G.

doi:10.1016/0002-9343(90)90290-t

Cited by 150 publications

(58 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…S. aureus follows CoNS as the major bacterium causing CLABSI, responsible for 14 to 41% of CLABSIs (624)(625)(626)(627). S. aureus CLABSI is associated with a 7 to 21% mortality rate (612,(628)(629)(630)(631)(632) and has been estimated to cost $9,830 to $14,136 per episode (633).…”

Section: Intravascular Catheter Infectionsmentioning

confidence: 99%

“…Clinical features of CLABSI are usually nonspecific. Fever, erythema, tenderness, induration, and/or purulence at the catheter insertion site may suggest catheter infection (628,630,632,640). Purulence at the catheter insertion site is much more common in CLABSIs due to S. aureus than in those due to Gram-negative rods (50% versus 2.4%; P Ͻ 0.01) (641).…”

Section: Intravascular Catheter Infectionsmentioning

confidence: 99%

“…Complicated SAB associated with a vascular catheter should be managed with 4 to 6 weeks of therapy. In all cases of S. aureus CLABSI, removal of the infected catheter is associated with a higher cure rate and a lower mortality rate (629,632,647,652) and should be regarded as the standard of care (647). Rarely, catheter removal is sufficiently problematic in an individual patient with limited i.v.…”

Section: Intravascular Catheter Infectionsmentioning

confidence: 99%

See 2 more Smart Citations

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

et al. 2015

View full text Add to dashboard Cite

SUMMARY Staphylococcus aureus is a major human pathogen that causes a wide range of clinical infections. It is a leading cause of bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device-related infections. This review comprehensively covers the epidemiology, pathophysiology, clinical manifestations, and management of each of these clinical entities. The past 2 decades have witnessed two clear shifts in the epidemiology of S. aureus infections: first, a growing number of health care-associated infections, particularly seen in infective endocarditis and prosthetic device infections, and second, an epidemic of community-associated skin and soft tissue infections driven by strains with certain virulence factors and resistance to β-lactam antibiotics. In reviewing the literature to support management strategies for these clinical manifestations, we also highlight the paucity of high-quality evidence for many key clinical questions.

show abstract

Section: Intravascular Catheter Infectionsmentioning

confidence: 99%

Section: Intravascular Catheter Infectionsmentioning

confidence: 99%

Section: Intravascular Catheter Infectionsmentioning

confidence: 99%

See 1 more Smart Citation

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Among a broad spectrum of micro-organisms causing nosocomial bloodstream infections, including Gram-positive bacteria, Gram-negative bacilli and fungi, Staphylococcus aureus is the most frequent micro-organism isolated in iatrogenic injection therapy-related septicaemia [2,14,27,30] and staphylococcal septicaemia more frequently has a fatal outcome than septicaemia caused by other bacteria [1,10]. Such fatalities due to Staphylococcus aureus septicaemia have only been reported sporadically in the forensic medical literature [16,32].…”

Section: Introductionmentioning

confidence: 99%

“…For detailed information on the well-known factors influencing the prevalence, morbidity and mortality of nosocomially acquired septicaemia (e.g. type and duration of catheterization, the widespread use of antibiotics resulting in multiple antibiotic resistance, procedures of skin preparation before insertion of intravascular devices or regimens for catheter site care), we refer to the comprehensive clinical literature on these topics [7,10,14,15,17,21,22,27,30,31].…”

Section: Introductionmentioning

confidence: 99%

Iatrogenic Staphylococcus aureus septicaemia following intravenous and intramuscular injections: clinical course and pathomorphological findings

Tsokos

Püschel

1999

International Journal of Legal Medicine

View full text Add to dashboard Cite

The clinical course, autopsy and histological findings are presented from three (one 33-year-old female and two males aged 26 and 56) fatalities resulting from injection therapy which has produced Staphylococcus aureus septicaemia. The autopsies were performed within 2-4 days postmortem. No primary focus other than the insertion site of the peripheral venous catheters or the intramuscular injections, representing the initial entry site of Staphylococcus aureus, could be identified. Death was attributed directly to the staphylococcal infection as a result of iatrogenic injection therapy for the treatment of a non-severe underlying illness (premature labour pains, acute loss of hearing, lumbago). The forensic diagnosis of Staphylococcus aureus septicaemia following iatrogenic injections has to be critically evaluated and can be established routinely in cases with delayed autopsy only when no other cause of death is revealed by autopsy, no apparent source of infection other than the insertion site can be detected and careful attention is paid to histological and bacteriological findings. All doubtful cases of nosocomial bloodstream infections with fatal outcome should undergo an immediate autopsy. In cases of very early forensic involvement microbiological investigations, including phagotyping, molecular biological characterization and identification of bacterial toxins from micro-organisms out of appropriate specimens obtained postmortem, could be efforts of potential evidential value regarding the aetiological proof. To optimize aetiopathogenetic conclusions concerning a causal relationship between iatrogenic injections and septic complications, the medicolegal investigation should also include an interdisciplinary co-operation with consultants from other relevant fields (e.g. microbiology and hygienics).

show abstract

Staphylococcus aureus catheter-associated bacteremia. Minimal effective therapy and unusual infectious complications associated with arterial sheath catheters

Malanoski

Samore

Pefanis

et al. 1995

Archives of Internal Medicine

View full text Add to dashboard Cite

show abstract

Staphylococcus aureus bacteremia in patients with Hickman catheters

Cited by 150 publications

References 21 publications

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

Iatrogenic Staphylococcus aureus septicaemia following intravenous and intramuscular injections: clinical course and pathomorphological findings

Staphylococcus aureus catheter-associated bacteremia. Minimal effective therapy and unusual infectious complications associated with arterial sheath catheters

Contact Info

Product

Resources

About