Staphylococcal Osteomyelitis of the Spine

Butler, E. C. B.; Blusger, I.N.; Perry, KennethM.A.

doi:10.1016/s0140-6736(00)61102-9

Cited by 18 publications

(2 citation statements)

References 2 publications

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“…In industrialized countries, pyogenic SD is the most frequent form and other presentations are exceptional. In the time before the use of antibiotics, mortality due to pyogenic D and SD reached 90% [ 8 ]. Currently, due to better diagnostic tools and improvements in medical and surgical treatment, mortality is significantly reduced and is lower than 5%.…”

Section: Introductionmentioning

confidence: 99%

Infectious Discitis and Spondylodiscitis in Children

Principi

Esposito

2016

IJMS

138

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In children, infectious discitis (D) and infectious spondylodiscitis (SD) are rare diseases that can cause significant clinical problems, including spinal deformities and segmental instabilities. Moreover, when the infection spreads into the spinal channel, D and SD can cause devastating neurologic complications. Early diagnosis and treatment may reduce these risks. The main aim of this paper is to discuss recent concepts regarding the epidemiology, microbiology, clinical presentation, diagnosis, and treatment of pediatric D and SD. It is highlighted that particular attention must be paid to the identification of the causative infectious agent and its sensitivity to antibiotics, remembering that traditional culture frequently leads to negative results and modern molecular methods can significantly increase the detection rate. Several different bacterial pathogens can cause D and SD, and, in some cases, particularly those due to Staphylococcus aureus, Kingella kingae, Mycobacterium tuberculosis, Brucella spp., the appropriate choice of drug is critical to achieve cure.

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Section: Introductionmentioning

confidence: 99%

Infectious Discitis and Spondylodiscitis in Children

Principi

Esposito

2016

IJMS

138

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“…Risk factors for spinal infection include increasing age, diabetes, renal failure, intravenous drug abuse, immunodeficiency states and the presence of an extra-spinal source of infection [1][2][3][4][5][6][7][8]. In the pre-antibiotic era, spondylodiscitis carried a mortality rate of between 25 and 100% [5,9]. Since that time, a majority of spinal infections have been effectively managed with antibiotics alone, and surgery has only been required when there is a failure to respond to antibiotics (with the potential need for an open biopsy) or when there are significant or progressive neurological deficits, spinal instability or deformity [6,8].…”

Section: Introductionmentioning

confidence: 99%

Veillonella spondylodiscitis in a healthy 76-year-old lady

et al. 2011

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Purpose To report a case of Veillonella spondylodiscitis in a healthy 76-year-old lady. Methods A previously healthy 76-year-old lady presented with worsening axial back pain at the thoracolumbar junction, fever and loss of weight. Examination revealed deep tenderness over the thoracolumbar junction with painful and restricted spinal movements. The lower limb motor power, sensation and reflexes were normal. Results Radiographs of the lumbosacral spine showed evidence of spinal instability with lateral translation and loss of disc space at L1-L2. MRI scans revealed fluid intensity within the L1-L2 disc with infective debris elevating the posterior longitudinal ligament and narrowing the spinal canal. Both tissue and blood cultures were positive for the anaerobic organism, Veillonella. A staged anterior-posterior spinal surgery followed by an extended course of antibiotics resulted in the clinical improvement and normalisation of blood parameters. A review of the literature on Veillonella infections is also presented. Conclusion The aim of this report is to bring Veillonella spondylodiscitis to the attention of spinal surgeons and infectious disease specialists and discuss the management options.

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Pyogenic Vertebral Osteomyelitis

Stone¹,

Bonfiglio²

1963

Arch Intern Med

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Staphylococcal Osteomyelitis of the Spine

Cited by 18 publications

References 2 publications

Infectious Discitis and Spondylodiscitis in Children

Infectious Discitis and Spondylodiscitis in Children

Veillonella spondylodiscitis in a healthy 76-year-old lady

Pyogenic Vertebral Osteomyelitis

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