Staphylococcal Infections and the Problem of Antibiotic-Resistant Staphylococci

Antibiotics: Their application in veterinary practice

“…Staphylococci are the bacteria which most rapidly produce resistant strains; ·the extent to which this occurs is related tQ both the concentration of the particular antibiotic and to the frequency with which they are exposed to it. This point is clearly illustrated ion Ta-ble 2, which is derived from data published by Spink (1954) showing results of sensitivity tests 'On staphylococci in the years 1951 to 1953 at the University of Minnesota Clinics. (Spink, 1954) In 1951 and 1952, the -tetracyclines (Aureomycin and Terramycin) were first used extensively in the U.S.A., and it is evident from the table that there was an increase in resistance to these ~rugs.…”

“…This point is clearly illustrated ion Ta-ble 2, which is derived from data published by Spink (1954) showing results of sensitivity tests 'On staphylococci in the years 1951 to 1953 at the University of Minnesota Clinics. (Spink, 1954) In 1951 and 1952, the -tetracyclines (Aureomycin and Terramycin) were first used extensively in the U.S.A., and it is evident from the table that there was an increase in resistance to these ~rugs. Moreover, the rate of development of resistance to erythromycin appears to be rapid, in so far as there was an increase in resistance from nil to 18 per cent.…”

Choice of Antibiotics in the Treatment of Common Infections

“…The inadequacies of even the best therapy are indicated by a recent report of an over-all mortality rate of about 50 per cent in cases of bacteremic staphylococcal infections. 12 Acute staphylococcal endocarditis, an increasingly common complication of staphylococcal infections, adds greatly to the problems of therapy.…”

Aspectos gerais das septicemias e bacteriemias estafilocócicas no adulto

“…que estudam o problema das infecções: 1) Estafilococos; 2) G ram negativos (28,15,3,46,6,42, Dentro do espectro das doenças esta- 35,44,1,24,45). íilccócicas, as septicemias são, sem nenhuÊstes tipos de germes pedem produzir ma dúvida, as de maior gravidade como doenças graves e mortais, não só do ponto atesta a alta m ortalidade atingida, inclu-de vista prim ário, como podem acometer indo estatísticas recentes (12,39,32,9).…”