“…Among different treatment strategies used in the treatment of TMD, transcutaneous electrical nervous stimulation (TENS) has been proposed (Jankelson, 1969;Jankelson and Swain, 1972;Talley et al, 1990): it is mainly used for the antalgic effect that could produce in symptomatic patients and for the positive relaxing effect that is exerted in the masticatory muscles (Gold et al, 1983); however, the antalgic effect of TENS application is still a debated question, since contrasting results have been reported in literature and the possibility of a placebo effect has been suggested (Oosterhof et al, 2008;Rakel and Frantz, 2003;Rakel et al, 2010). In addition, the effect of TENS application on sEMG activity of masticatory muscles has been poorly investigated: indeed, only two study (Rodrigues et al, 2004;Cooper and Kleinberg, 2008) investigated the effect of TENS on sEMG activity of masticatory muscles, reporting a reduced sEMG activity of hyperactive muscles and an increased activity of masseter muscles during maximum voluntary clenching (Rodrigues et al, 2004); however, these studies used a long TENS application time (from 45 to 60 min) in symptomatic patients; furthermore, none of the studies analyzed kinesiographic changes after TENS application.…”