Standardized Quantification of Vagal Denervation by Extracardiac Vagal Stimulation during Second Generation Cryoballoon ablation: a Vein per Vein Analysis

Murtaza, Ghulam; Young, Daisy; Akella, Krishna; Gopinathannair, Rakesh; Lakkireddy, Dhanunjaya; Shah, Alap

doi:10.4022/jafib.2233

Cited by 1 publication

(2 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A previous study that quantified substrate modification in the LA using high‐density mapping, demonstrated that approximately 60% of the LA posterior wall was modified by CBA in the LA roof line 4 . CBA in the LA roof may also affect the ganglionated plexus 18 . These additional effects of CBA may contribute to the high AF‐free survival rate.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A novel catheter ablation strategy for non‐paroxysmal atrial fibrillation combining cryoballoon, radiofrequency, and Marshall‐vein ethanol ablations

Hayasaka

Sasaki

Shirai

et al. 2023

Pacing Clinical Electrophis

View full text Add to dashboard Cite

Backgrounds Catheter ablation for non‐paroxysmal atrial fibrillation (non‐PAF) remains challenging and more effective strategy has been required to reduce postoperative arrhythmia recurrences. This study aims to investigate the efficacy and safety of a novel extensive ablation strategy for non‐PAF, that is based on a combination of cryoballoon (CBA), radiofrequency (RFA), and Marshall‐vein ethanol ablations (EA‐VOM). Methods The study was a single‐center, retrospective observational study. We enrolled 171 consecutive patients who underwent de‐novo catheter ablation for non‐PAF under conscious sedation with a novel extensive ablation strategy that included CBA for pulmonary vein isolation (PVI) and left atrial roof ablation (LARA), RFA for mitral isthmus (MI) ablation, superior vena cava isolation, and other linear ablations and EA‐VOM. Recurrence of atrial arrhythmias over 1 year, procedure outcomes, and procedure‐related complications were investigated. Results A total of 139 (81.3%) patients remained in sinus rhythm during 1‐year follow‐up. Of the 139 patients, 51 patients (29.8%) received antiarrhythmic drugs. The mean procedure time was 204 ± 45 min. PVI and LARA ablation by CBA and MI block by RFA and EA‐VOM were completed in 171 (100%) and 166 (97.1%) patients, respectively. No serious procedure‐related complications were observed except for one case of delayed pericardial effusion. Conclusion Approximately 80% of the study patients were AF‐free during 1‐year follow‐up period after a single procedure based on the novel extensive ablation strategy combining CBA, RFA, and EA‐VOM. This strategy for non‐PAF may be preferred in terms of maintenance of sinus rhythm, safety even in high‐risk patients, and relatively short procedure time.

show abstract

Section: Discussionmentioning

confidence: 99%

“…4 CBA in the LA roof may also affect the ganglionated plexus. 18 These additional effects of CBA may contribute to the high AF-free survival rate.…”

Section: La Roof Ablation With Cryoballoonmentioning

confidence: 99%