“…Aloe contains two major active materials: one is the aloe polysaccharides presenting in aloe filet; the other is anthraquinone derivatives existing in the leaves of different aloe plants [3]. The major constituents have multiple pharmacological actions including laxative, anti-bacterial, anti-inflammation, hemostatic, and antispasmodic [4][5][6][7][8][9]. These constituents are isolated by various extraction methods such as pressurized hot water extraction [10], ultrasonic and microwave extraction [11], supercritical CO 2 extraction [12], and pressurized liquid extraction [13].…”