Standard molar enthalpies of formation of 5- and 6-nitroindazole

Experimental and computational study of the energetics of 5- and 6-aminoindazole

“…As can be seen, the positive value of the increment shows that the amino group, a donor group, causes a destabilization in the indazole molecule. The opposite effect was verified for the introduction of the nitro group, which results in a negative increment [6]. This could allow us to expect that donor groups destabilize the indazole molecule, possibly due to the reduction of the electronic delocalization, while the withdrawing groups provide an increase of the delocalization and, consequently, the stabilization of the molecule.…”

“…The results for 5-and 6-nitroindazole were already published and it was concluded that the introduction of the nitro group has a stabilization effect in the indazole molecule and that this effect is similar, whether the nitro group is in position 5 or 6 [6].…”