Staged stereotactic irradiation for acoustic neuroma. Neurosurgery 2005;56:1254-1263

Radiation Therapy and Radiosurgery for Vestibular Schwannomas:

“…In addition, the mean number of isocenters used increased to 8 (range, [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20], reflecting the overall improved dose conformality. Over this interval, there were no cases of new facial weakness, trigeminal symptoms occurred in less than 4% of patients, and hearing loss was reduced to 23%.…”

“…Hypofractionated (multisession) SRS procedures for patients with VS generally use 18 to 21 Gy in 3 daily fractions up to 20 to 25 Gy in 5 daily fractions. 8,9 case series (level 4 evidence) and case-control series (level 3 evidence) [18][19][20][21][22][23][24][25][26] up to more recent prospective cohort studies (level 2 evidence). [27][28][29] The best evidence (levels 2 and 3) shows improved cranial nerve outcomes in shortterm follow-up (<5 years) for patients with VS using SRS compared with MS. Two prospective studies have shown that MS is associated with a decline in quality-of-life (QOL) measures, whereas SRS did not affect patients' day-to-day living in a significant manner.…”