Stability of plasma-polymerized allylamine films with sterilization by autoclaving

Abstract

The stability of plasma-polymerized allylamine films with autoclaving sterilization cycles was investigated. Polymerized films were deposited under pulsed plasma conditions using two different duty cycles to provide surfaces having different initial amino group concentrations. The film properties were analyzed by XPS and water contact angle measurements before and after autoclaving. The reactions of these surfaces with trifluoroacetic anhydride provided quantitation of the amino surface concentrations before and after autoclaving. In general, the plasma-polymerized films exhibit good stability vis à vis the autoclaving process, with relatively high retention of the surface amino groups. The results of this work are of specific value with respect to tissue culture studies in which surface modifications involving the introduction of amino groups have been shown to have high efficacy in promoting cell growth. The results obtained suggest that the simple one-step plasma treatment process is a viable alternative to the more cumbersome surface modification procedures currently employed to introduce amino groups in these tissue culture studies.

Capacitance-voltage characterization of pulsed plasma polymerized allylamine dielectrics for flexible polymeric field effect transistors

“…More details on the chemical composition and stability of plasma-generated polyallylamine films have recently been published. 17,18 Figure 3 shows C-V responses for PA1 and PA2. The high-frequency (HF) response for both PA1 and PA2 clearly shows accumulation and depletion regions that are typical in HF Si MOSFET characteristics.…”

Plasma-surface modification of biomaterials

“…It can, thus, be concluded that the rfGD plasma treatment is the best technique for sterilizing polyester devices in tissue-engineering applications because it does not alter the three-dimensional morphology of the scaffolds. Calderon et al investigated the stability of plasma-polymerized allyamine films with an autoclaving sterilization cycle [149]. Polymerized films are deposited under pulsed plasma conditions using two duty cycles to give rise to surfaces having different initial amino group concentrations.…”

Hydrophilic Fluorocarbon Coatings via Plasma Enhanced-Chemical Vapour Co-Deposition of Acrylic Acid and Hexafluoropropylene Oxide

“…Like all the PE-CVD processes, the proposed approach has several advantages, e.g., it is solvent free and ecofriendly, it allows the deposition of strongly adhered pinhole-free polymer films on different substrates with several geometries or shapes, the treatment is performed at low temperature with minimal thermal stress, resistance to degradation and with the possibility to treat also thermolabile materials (e.g., paper, polymers, etc.) [14][15][16][17][18][19][20]. At the best of our knowledge, the co-deposition by PE-CVD of fluorocarbon and a carboxylic acid for the preparation of hydrophilic fluorinated polymer has never been reported.…”