Stability-indicating capillary gas—liquid chromatographic assay of dicyclomine hydrochloride in some pharmaceutical formulations

Reversed Phase High Performance Liquid Chromatography Method Development and Validation for Simultaneous Estimation of Dicyclomine Hydrochloride, Paracetamol and Mefenamic Acid in Bulk and Tablet Dosage Form

“…Literature survey reveals that many spectrophotometric methods [5][6][7][8][9][10], high performance liquid chromatography (HPLC) [11][12][13][14][15][16][17][18][19][20][21][22][23][24], high performance thin layer chromatography [25][26][27][28][29], liquid chromatography-mass spectrometry [30], and GC [31] based methods have been reported for estimation of these drugs alone as well as in combination with other drugs in pharmaceutical dosage forms. Reversed phase (RP-HPLC) method offer significant economic advantages over the techniques cited above.…”

Improving the detection limits of antispasmodic drugs electrodes by using modified membrane sensors with inner solid contact

“…They have been used for treatment of irritable bowel syndrome, gastrointestinal diseases, biliary dyskinesia, nephrolithiasis, gynecologiicial diseases and vasomotor diseases associated with smooth muscle spasms [10]. The reported methods for determination of the antispasmodic drugs; dicyclomine [11,12], mebeverine [13,14] and drotaverine [15,16] are mainly chromatographic, which in spite of their high sensitivities, are very expensive, involve the use of complex procedures with several sample manipulations and requiring long analysis time.…”