The hardware under test (HUT) in a power hardware in the loop (PHIL) implementation can have a significant effect on overall system stability. In some cases, the system under investigation will be unstable unless the HUT is already connected and operating. Accordingly, initialization of the real-time simulation can be difficult, and may lead to abnormal parameters of frequency and voltage. Therefore, a method to initialize the simulation appropriately without the HUT is proposed in this contribution. Once the initialization is accomplished a synchronization process is also proposed. The synchronization process depends on the selected method for initialization and therefore both methods need to be compatible. In this contribution, a recommended practice for the initialization of PHIL simulations for synchronous power systems is presented. Experimental validation of the proposed method for a Great Britain network case study demonstrates the effectiveness of the approach.