St John's wort for major depression

Linde, Klaus; Berner, Michael; Kriston, Levente

doi:10.1002/14651858.cd000448.pub3

Cited by 336 publications

(299 citation statements)

References 94 publications

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“…[1] HP has been used for medicinal purposes for centuries. It is used for the treatment of mild to moderate depression, [2] healing wounds (acute and contused injuries), [3] first-degree burns, [3] relieving myalgia (muscle pain, [3] seasonal affective disorder, [4] obsessive-compulsive disorder, [5] pre-menstrual syndrome, [6] menopause, [7] EXPERIMENTAL STUDY…”

Section: Introductionmentioning

confidence: 99%

Investigation of Acute Effects of Hypericum Perforatum (Kantaron) Treatment in Experimental Thermal Burns and Comparison with Silver Sulfadiazine Treatment

Kıyan¹

2015

Ulus Travma Acil Cerrahi Derg

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Section: Introductionmentioning

confidence: 99%

Investigation of Acute Effects of Hypericum Perforatum (Kantaron) Treatment in Experimental Thermal Burns and Comparison with Silver Sulfadiazine Treatment

Kıyan¹

2015

Ulus Travma Acil Cerrahi Derg

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“…Two examples of CAM treatments that have become (more) accepted by conventional medicine are St. John´s wort and acupuncture for specific indications. St. John´s wort, for more than 90 years used in anthroposophic medicine, has become part of the conventional guidelines for the treatment of depression, based on scientific evidence from randomized controlled trials [6]. Hopton and McPherson [7] conclude on the basis of a systematic review of pooled data from meta-analyses that acupuncture is more than a placebo for commonly occurring chronic pain conditions.…”

Section: Introductionmentioning

confidence: 99%

Patients whose GP knows complementary medicine tend to have lower costs and live longer

Kooreman¹,

Baars²,

Malek³

2011

Deutsche Zeitschrift für Akupunktur

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Standard-Nutzungsbedingungen:Die Dokumente auf EconStor dürfen zu eigenen wissenschaftlichen Zwecken und zum Privatgebrauch gespeichert und kopiert werden.Sie dürfen die Dokumente nicht für öffentliche oder kommerzielle Zwecke vervielfältigen, öffentlich ausstellen, öffentlich zugänglich machen, vertreiben oder anderweitig nutzen.Sofern die Verfasser die Dokumente unter Open-Content-Lizenzen (insbesondere CC-Lizenzen) zur Verfügung gestellt haben sollten, gelten abweichend von diesen Nutzungsbedingungen die in der dort genannten Lizenz gewährten Nutzungsrechte. www.econstor.eu (25), homeopathy (28) and anthroposophic medicine (26). Patients whose GP has additional CAM training have 0 to 30 percent lower healthcare costs and mortality rates, depending on age groups and type of CAM. The lower costs result from fewer hospital stays and fewer prescription drugs. Since the differences are obtained while controlling for confounders including neighborhood specific fixed effects at a highly detailed level, the lower costs and longer lives are unlikely to be related to differences in socioeconomic status. Possible explanations include selection (e.g. people with a low taste for medical interventions might be more likely to choose CAM) and better practices (e.g. less overtreatment, more focus on preventive and curative health promotion) by GPs with knowledge of complementary medicine. More controlled studies (replication studies, research based on more comprehensive data, cost-effectiveness studies on CAM for specific diagnostic categories) are indicated. Terms of use: Documents in D I S C U S S I O N P A P E R S E R I E SJEL Classification: I11, I12

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“…perforatum, St John's wort in English language, is native to Europe but exhibits spontaneous distribution across the world particularly in temperate and subtropical regions including China, Turkey, Ukraine, Russia, India, Canada and the USA (Butterweck and Schmidt, 2007). To date, several studies have been conducted on antidepressant effects of H. perforatum in mice and humans that confirmed the potential therapeutic effects of this plant (Butterweck and Schmidt, 2007;Carpenter et al, 2008;Linde et al, 2008). H. perforatum extract contributes to not only treating depression but also preventing its recurrence.…”

Section: Hypericum Perforatummentioning

confidence: 94%

A review on antidepressant effect of medicinal plants

Rabiei

2017

Bangladesh J Pharmacol

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<p class="Abstract">Depression is a life-threatening, debilitating, and common disease affecting different segments of community. Chemical and synthetic drugs available to treat this disease cause many adverse effects and may lead to complete recovery in only 50% of patients. At the same time, medicinal plants have been reported to exert optimal pharmacological effects in treating depression in different models. In this review, the relevant articles indexed in the reliable databases PubMed, PubMed central, Scopus and Web of Science were review-ed. The review indicated that most medicinal plants exerted antidepressant effects through synaptic regulation of serotonin, noradrenaline, and dopamine, regulating activity of hypothalamic-pituitary-adrenal axis, reinfor-cing anti-oxidant defense system, and decreasing inflammatory mediators. The medicinal plants and their active compounds can relieve depression through different pathways and hence are considered a new source to produce antidepressants.</p>

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St John's wort for major depression

Cited by 336 publications

References 94 publications

Investigation of Acute Effects of Hypericum Perforatum (Kantaron) Treatment in Experimental Thermal Burns and Comparison with Silver Sulfadiazine Treatment

Investigation of Acute Effects of Hypericum Perforatum (Kantaron) Treatment in Experimental Thermal Burns and Comparison with Silver Sulfadiazine Treatment

Patients whose GP knows complementary medicine tend to have lower costs and live longer

A review on antidepressant effect of medicinal plants

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