Squamous Odontogenic Tumor Causing Erosion of the Lingual Cortical Plate in the Mandible: A Report of 2 Cases

Kim, King; Mintz, Sheldon; Stevens, Jeffrey

doi:10.1016/j.joms.2006.05.051

Cited by 26 publications

(35 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In maxilla, SOT occurred most commonly in canine-first premolar area. [7] Our case is unique in that it is the first case reported in the Indian literature and second ever case to occur between the roots of central and lateral incisors in the anterior segment of the mandible. Hence, the most common location for development of an SOT in the maxilla is anterior region and posterior in case of mandible with almost equal propensity to occur in both the jaws.…”

Section: Discussionmentioning

confidence: 94%

Squamous odontogenic tumor: A case report and review of literature

Badni

Nagaraja

Kamath

2012

J Oral Maxillofac Pathol

View full text Add to dashboard Cite

The squamous odontogenic tumor (SOT) is a rare, benign, locally infiltrative neoplasm of the jaws that appears to originate from the rests of Malassez, gingival surface epithelium or from remnants of the dental lamina. SOT was first described by Pullon et al. (1975). Since then there has been paucity in the number of reported cases, especially in the Indian subcontinent. The tumor is often asymptomatic, although it can present with symptoms of pain and tooth mobility. The characteristic radiographic appearance is that of a triangular-shaped unilocular radiolucency associated with the roots of erupted, vital teeth and has a predilection for the anterior maxilla and the posterior mandible. Histologically, the tumor is characterized by the formation of variably sized nests and cords of uniform, benign-appearing, squamous epithelium with occasional vacuolization and keratinization. We report a case of SOT occurring in a 58-year-old male in the anterior mandible with unusual localization and appearance.

show abstract

Section: Discussionmentioning

confidence: 94%

Squamous odontogenic tumor: A case report and review of literature

Badni

Nagaraja

Kamath

2012

J Oral Maxillofac Pathol

View full text Add to dashboard Cite

show abstract

“…This enzyme regulates tumor invasion and dissemination by modulating extracellular matrix. Mutation of this gene is linked to the development of SOT [37]. Moreover, studies show that Notch receptors 1, 3, 4 and their ligands, Jagged1 and Delta1 may play a role in the cellular differentiation and transformation events of epithelial rests leading to the development of SOT [10].…”

Section: Discussionmentioning

confidence: 99%

“…Males are slightly more affected than females (1.2:1) and no ethnic predilection is observed [36]. In the mandible, the posterior region is more commonly affected while maxillary lesions have a tendency to occur in the anterior-canine to premolar area [36,37,41]. In rare instances, maxillary tumors may exhibit a locally aggressive behavior [36,46].…”

Section: Discussionmentioning

confidence: 99%

“…SOT may present as asymptomatic or symptomatic lesions. [37,41]. The symptomatic lesions are associated with bone expansion and teeth mobility [37].…”

Section: Discussionmentioning

confidence: 99%

“…In addition, SOT may also present as multilocular radiolucencies [5,23]. The peripheral variant may produce 'saucerization' of the underlying bone as a result of localized tumor pressure [4,37,42]. Furthermore, the radiographic appearance of SOT may vary from well to illdefined radiolucencies with or without cortication [5,14,43].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Multicentric Squamous Odontogenic Tumor: A Case Report and Review of the Literature

Elmuradi

Mair

DeSantis

et al. 2016

Head and Neck Pathol

View full text Add to dashboard Cite

Squamous odontogenic tumor (SOT) is a rare benign epithelial odontogenic neoplasm of the jaws. Both intraosseous and peripheral SOTs have been described in the English language literature. While most intraosseous SOTs occur as solitary lesions, a multicentric variant has also been previously described. Although the radiographic and microscopic features are identical for both solitary and multicentric clinical presentations, there are three significant differences between them. More specifically, multicentric SOT presents at an earlier age (third decade of life), has a slightly higher male to female ratio than the solitary type and has a marked predilection for African-Americans. Here we document the eighth reported case of multicentric SOT, which was diagnosed in a 43-year-old AfricanAmerican male. In addition, we feature focal sebaceous metaplasia, a heretofore unknown microscopic feature of SOT. Clinical, radiological, and histopathological findings are discussed. The differential diagnosis, biological behavior and management modalities for SOT are also addressed.

show abstract