Squamous Cell Carcinoma of the Conjunctiva

Prevalence of HIV seropositivity among patients with squamous cell carcinoma of the conjunctiva

“…Squamous cell carcinoma although, the most frequently encountered conjunctival malignancy is still an uncommon tumour of the conjunctiva [1,6] . The exact cause is not known.…”

“…The incidence of this neoplasm worldwide varies from 0.02 to 3.5 per 100 000 [6] . There have been reports documenting a recent increase in its incidence especially in equatorial Africa [7,8] .…”

Conjunctival Squamous Cell Carcinoma, A Rare Entity: Case Report of 2 Cases

“…Squamous cell carcinoma (SCC) arising from conjunctiva is an uncommon disease world wise, the incidence of which varies from 0.02 to 3.5 per 100 000 [1,2]. Since the 1980s, the number of patients presenting with squamous cell carcinoma of the conjunctiva has been increasing exponentially [2,3].…”

“…Even before the term ocular surface squamous neoplasia (OSSN) was introduced to encompass the spectrum of conjunctival and corneal intraepithelial neoplasia (CIN) and SCC [1][2][3][4], published series often included both intraepithelial and invasive squamous neoplasia. It is difficult to distinguish dysplasia, Carcinoma in situ (CIS), and SCC on clinical grounds alone.…”

Altered gene expression in conjunctival squamous cell carcinoma

“…1 Squamous carcinomas are the commonest non-pigmented malignancies of the conjunctiva, with a yearly incidence that ranges from 0.02 to 3.5 per 100 000. 2 One of the main risk factors is exposure to the high ultraviolet (UV-B) light, thus the incidence of conjunctival squamous cell carcinoma has a geographic variability and is highest at shorter distances from the equator. Another important risk factor is immunosuppression, often due to human immunodeficiency virus (HIV) infection.…”