Squamous cell carcinoma of the oral cavity in young patients under 40 years

Changing Trends in Oral Squamous Cell Carcinoma with Particular Reference to Young Patients: 1971–2006. The Emory University Experience

“…There are five previous studies reported in the literature examining OSCC in patients 40 years of age and younger [2,3,[13][14][15]. In many ways our findings are similar to those of prior studies.…”

“…In many ways our findings are similar to those of prior studies. In our study the average age at presentation of the young patient subset was 32.5 years, similar to the average ages of 31.7 years reported by Son and Kapp [15] and 34.8 years reported by Martin-Granizo et al [2]. The two youngest patients in our study were 19 years of age at presentation.…”

“…Indeed several other authors examining OSCC in a young population also have found the mobile tongue to be the most common site of occurrence [2,3,[13][14][15]. Martin-Granizo et al reported 29% of cases affecting the tongue [2]. Slightly higher proportions of cases affecting the mobile tongue were found by other authors (e.g., 38% by Hart et al, 41% by Son and Kapp, 45% by Mackenzie et al) [13,15,16].…”

“…In our study, there was a significantly greater proportion of oral cancer cases involving the mobile tongue in the young cohort compared to patients C40 years old (62.1% vs. 27.4%, P \ 0.00001). Indeed several other authors examining OSCC in a young population also have found the mobile tongue to be the most common site of occurrence [2,3,[13][14][15]. Martin-Granizo et al reported 29% of cases affecting the tongue [2].…”

“…Among young persons, the occurrence of OSCC is rare, representing from 0.9 to 2.7% of all cases [2]. However, several recent reports suggest an increasing incidence of this disease among young persons in many regions of the world-a trend which is particularly concerning given the overall stabilization or even decline in incidence rates for head and neck cancer in general [3][4][5].…”