1973
DOI: 10.1001/archderm.107.1.80
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Spread of tumors to the skin

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Cited by 106 publications
(77 citation statements)
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“…Thus, the internists' reviews do not concur with dermatologists' studies (8,10). Clinical manifestations of skin metastases were classified as nodular, inflammatory, and sclerodermoid metastatic lesion by Brownstein and Helwig (1). Generally, the nodular type is the result of hematogenous metastasis, and is likely to be most commonand multiple (3,4,12).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Thus, the internists' reviews do not concur with dermatologists' studies (8,10). Clinical manifestations of skin metastases were classified as nodular, inflammatory, and sclerodermoid metastatic lesion by Brownstein and Helwig (1). Generally, the nodular type is the result of hematogenous metastasis, and is likely to be most commonand multiple (3,4,12).…”
Section: Discussionmentioning
confidence: 99%
“…In the 1970s, Brownstein and Helwig reported that lung cancer as well as breast cancer werethe mostcommon cancers to metastasize to the skin (1,2). Since 1993, the mortality from lung cancer has been the highest for malignancies in Japan, and recently it has been reported to be the most commoninternal malignancy to metastasize to the skin.…”
Section: Introductionmentioning
confidence: 99%
“…7 Generally, the nodular type represents metastasis by blood stream, the inflammatory type by lymph flow, and the sclerodermoid type by direct infiltration. 8 Remote skin metastases, especially if they appear before invasion of local lymph nodes, can be regarded as hematogenous metastases.…”
Section: Discussionmentioning
confidence: 99%
“…Cutaneous metastases often show a lesser degree of differentiation than those of the primary neoplasm. 7 In the experience of McKee, 9 a significant number of metastatic tumors in the skin show no distinctive histopathological features, and can only be reported as metastatic anaplastic carcinoma. Usually, pancreatic carcinomas metastasize rapidly to the lymphatic system by permeation, embolization, and retrograde spread in the presence of lymphatic obstruction.…”
Section: Discussionmentioning
confidence: 99%
“…Brownstein and Helwig classify clinical manifestations of skin metastases as nodular, inflammatory, and sclerodermoid metastatic lesions. 3 The scalp is a favorite site of cutaneous metastasis of lung cancers that accounts for 54% of all cutaneous metastases of this cancer. This finding can be explained by the rich blood flow in the scalp.…”
mentioning
confidence: 99%