Sporty Spots

Jenkinson, Helena; DiCicco, Beau

doi:10.1001/jamadermatol.2017.4694

JAMA Dermatol

2018

DOI: 10.1001/jamadermatol.2017.4694

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Sporty Spots

Helena Jenkinson

Beau DiCicco

Abstract: 2.Zwald FO, Brown M. Skin cancer in solid organ transplant recipients: advances in therapy and management, part I: epidemiology of skin cancer in solid organ transplant recipients.

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“…In recent years, cupping experienced a noticeable surge in interest in pain control in the field of sports medicine. 3 The color of the cupping mark as a predictive indicator of the effectiveness of cupping could enable the therapist to make evaluations and adjustments accordingly. 1 Nevertheless, some receivers of cupping consider the cupping marks harmful.…”

mentioning

confidence: 99%

Hemorphin-Based Analgesia: A Mechanism of Cupping Technique?

Song¹,

Wang²,

Song³

2023

JPR

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Background and Objective: Cupping is a time-honoured traditional healing modality for pain management and remains favoured by professionals and lay people across several cultures today. However, the analgesic mechanism of cupping is still poorly understood. In addition, clinical guidelines for standardized applications of cupping are currently lacking. The awareness of cupping marks has provoked curiosity about the connection between skin color changes and their benefit for local pain relief. Computer simulation is a promising approach for numerical modeling the cupping-evoked erythrocyte emigration. Quantitative proteomic profiling of cupping-induced blister fluid exhibited a significant decrease in the abundance of haemoglobin β subunit. This finding provides a critical clue to paint a novel picture of the mechanism behind cupping. The hemorphins are a set of non-classical opioid peptides derived from the proteolysis of haemoglobin β subunit. In the present study, a probable mechanism of hemorphin-based cupping analgesia is proposed. The hemorphin could also act as a potential biomarker for objective and timely quantitative clinical assessment of cupping in the management of pain conditions. A seminal theory may open a new avenue for future translational research on promoting the efficacy and safety of cupping analgesia. Conclusion:The local analgesic effect of cupping is probable in the context of haemoglobin degradation that bestows the appearance of hemorphins along with engaging opioid receptor signalling. Exploring the potential novel mechanism of cupping analgesia facilitates seeking non-pharmacologic pain interventions.

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confidence: 99%

Hemorphin-Based Analgesia: A Mechanism of Cupping Technique?

Song¹,

Wang²,

Song³

2023

JPR

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Bibliography of secondary sources on the history of dermatology: I. Journal articles in English

Parish

Hoenig

Grzybowski

et al. 2021

Clinics in Dermatology

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Sporty Spots

Abstract: 2.Zwald FO, Brown M. Skin cancer in solid organ transplant recipients: advances in therapy and management, part I: epidemiology of skin cancer in solid organ transplant recipients.

Cited by 2 publications

References 2 publications

Hemorphin-Based Analgesia: A Mechanism of Cupping Technique?

Hemorphin-Based Analgesia: A Mechanism of Cupping Technique?

Bibliography of secondary sources on the history of dermatology: I. Journal articles in English

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