Malaria is a serious, mosquito-borne, infectious disease that is caused by Plasmodium species. Plasmodium species are transmitted by infected female mosquitoes of genera that bite humans. These parasites grow within erythrocytes and are released by cyclic hemolysis. Malaria is distributed worldwide in endemic areas such as South America, Africa, and South Asia. South Korea was known to be an area endemic for P. vivax , and the reemergence of this disease has been reported along the western edge of the Demilitarized Zone since 1993.
1The main symptom of malaria is episodic fever. Abdominal symptoms of P. vivax malaria are usually mild and nonspecific and include abdominal pain or hepatosplenomegaly.
2, 3However, abdominal computed tomography (CT) findings of patients with P. vivax malaria are not well known. To the best of our knowledge, only a few sporadic case reports are found in the English literature.2-5 Malaria is still a worldwide lifethreatening infection and should be included in the differential diagnosis of a fever wherever malaria is present. Therefore, the purpose of this study was to investigate the abdominal CT findings of P. vivax malaria.This retrospective study was reviewed and approved by our institutional review board and patient consent was waived. During January 2004-February 2009, the medical records of 405 patients in our hospital who were confirmed as having P. vivax malaria by peripheral blood smear were obtained. Among them, 47 patients underwent an abdominal CT examination and 51 patients underwent abdominal ultrasonography because of gastrointestinal symptoms.Exclusion criteria were more than a three-day interval between the peripheral blood smear and CT scan (n = 8), nondigitalized images (n = 2), unavailable peripheral blood smear slides (n = 2), and monophasic CT (n = 1). Thus, our final study population was composed of 34 patients (24 men and 10 women, mean age = 48.1 years). All patients were completely cured by treatment with chloroquine and most patients were lost to further follow-up. Two patients underwent follow-up CTs for other reasons. One patient underwent a splenectomy for a spontaneous rupture. Two patients with a subcapsular hematoma were hemodynamically stable and were successfully managed with supportive care.We retrospectively searched and evaluated the medical records of 80 consecutive patients (40 men and 40 women, mean age = 48.7 years) among those who visited the emergency department with high fever (> 38.3°C), had negative results for a peripheral blood smear, and underwent bi-phasic abdominal CT. The causes of their fever were acute hepatitis (n = 17), acute pyelonephritis (n = 11), acute gastroenteritis (n = 9), cholecystitis (n = 9), liver abscesses (n = 8), and cholangitis (n = 5), and so on. All diagnoses were confirmed by available date in the form of image characteristics, pathologic results, and clinical courses. For the normal group, we also tested 120 consecutive persons (86 men and 34 women, mean age = 45.9 years) who visited a health promotion cente...