Spontaneous splenic rupture: A rare presentation of dengue fever

Mukhopadhyay, Mainak; Chatterjee, Nandini; Maity, Prasenjit; Patar, Kartik

doi:10.4103/0972-5229.126085

Cited by 10 publications

(15 citation statements)

References 8 publications

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“…Immediate splenectomy after exploration was done for 12 patients (70.6%) . Conservative treatment was used in five cases . However, two cases got painful recurrence, and the management was continued by delayed splenectomy …”

Section: Resultsmentioning

confidence: 95%

“…level was 25.6% (range: 12.2%‐49.8%, data available in 12 cases), while the median hemoglobin was 8.8 g/dl (range: 3.4‐14.3) (Table ). Coagulation profiles (prothrombin time and partial thromboplastin time) were reportedly in the normal range of three cases, while in one case, they were prolonged…”

Section: Resultsmentioning

confidence: 99%

“…Enlarged spleen (splenomegaly) was detected in seven cases (41.2%): in computed tomography (CT) scan, in ultrasonography (U/S), and direct measuring after splenectomy (Table ).…”

Section: Resultsmentioning

confidence: 99%

“…Most of splenic rupture cases were confirmed by contrasted or plain CT scan for acute abdominal symptoms ( n = 11; 64.7%), immediate CT in ( n = 9; 52.9%), and delayed CT in ( n = 2; 11.8%) (Table ). The major findings were persistent evidence of free fluid in peritoneal cavity (ascites) or hemoperitoneum ( n = 8; 72.7%), splenic hematoma or adherent thrombus ( n = 5; 45.5%), ruptured spleen ( n = 3; 27.3%), subcapsular hematoma ( n = 3; 27.3%), per‐capsular/per‐splenic effusion ( n = 3; 27.3%), and splenomegaly ( n = 3; 27.3%) …”

Section: Resultsmentioning

confidence: 99%

“…Prior‐laparotomy resuscitation was managed in eight cases by using packed red blood cells or/with intravenous fluids (normal saline, colloid, or crystalloid) …”

Section: Resultsmentioning

confidence: 99%

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Systematic review of spontaneous splenic rupture in dengue‐infected patients

Radwan

Khattab

Mahmoud

et al. 2019

Reviews in Medical Virology

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Summary Dengue infection varies from a mild febrile form to more severe disease with plasma leakage, shock, and multiorgan failure. Several serious complications such as cardiomyopathy, encephalopathy, encephalitis, hepatic damage, and neural manifestations cause organ damage in dengue infection. Splenic rupture, a less well known but life‐threatening complication, can occur in dengue. The mechanism of splenic rupture in dengue is still unclear. Optimal therapeutic management is required to save the lives of patients with this complication. The objective of this study was to conduct a systematic review of studies documenting the development of spontaneous nontraumatic splenic rupture in patients with dengue infection. In March 2018, a search was conducted systematically in nine electronic databases, in addition to hand‐ searching. A total of 127 references were exported to Endnote; 47 references remained after removing duplicates. Finally, 16 reports met the inclusion criteria and represented 17 cases. All articles were evaluated and data extracted according to predefined criteria: number of cases, age, sex, severity of dengue disease, days of illness before admission, methods of definitive diagnosis, timing of the event, and management and outcome. A total of 17 individual patients including 13 males and four females were found. Most of the patients were young adults (ranging from 20 to 52 years) and diagnosed with computed tomography scan and managed with splenectomy. Four cases were fatal. Pathological splenic rupture in dengue is a rare, life‐threatening condition where timely management can achieve a favorable outcome.

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Section: Resultsmentioning

confidence: 95%

Section: Resultsmentioning

confidence: 99%

“…Enlarged spleen (splenomegaly) was detected in seven cases (41.2%): in computed tomography (CT) scan, in ultrasonography (U/S), and direct measuring after splenectomy (Table ).…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Prior‐laparotomy resuscitation was managed in eight cases by using packed red blood cells or/with intravenous fluids (normal saline, colloid, or crystalloid) …”

Section: Resultsmentioning

confidence: 99%

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