Spontaneous resolution of a delayed granulomatous reaction to cosmetic tattoo

Abstract

A 27-year-old woman presented with linear, flesh-colored papules along her vermillion borders, 4 years after a cosmetic lip tattoo was applied. A biopsy of the lesion was performed and histology showed it to be a granulomatous reaction surrounding the tattoo pigment. Following the biopsy, the lesions began to resolve spontaneously within 4 weeks and were not noticeable at a follow-up review. Granulomatous reactions are rare after cosmetic facial tattoos and may respond to topical corticosteroids or laser ablation. We present a unique report of a delayed granulomatous reaction to a cosmetic tattoo completely resolving without any specific treatment.

Nonmelanoma skin cancer in India: Current scenario

“…There are uncommon reports of SCC arising from burns scar and presenting as cutaneous horn,[33] SCC in situ arising in smallpox vaccination scar,[34] etc. Tumors arising from scars are usually aggressive, and local recurrences are common.…”

Delayed Granulomatous Reaction after Oral Piercing during Thaipusam

“…There have also been reports of spontaneous resolution of granulomatous reaction in a cosmetic tattoo8. Our patient responded well after one intralesional triamcinolone injection, and has been planned for monthly injections until the lesions regress completely.…”

Generalized lichenoid tattoo reaction with spontaneous resolution after skin biopsy

“…Spontaneous resolution of a granulomatous reaction to tattoos has been reported in one case. 2 However, in that case, the tissue reaction was localized to a cosmetic lip tattoo. Our patient developed a generalized lichenoid tattoo reaction, which resolved spontaneously after a skin biopsy.…”

“…A possible explanation for the resolution of the cutaneous reaction may be due to the inflammatory process and wound healing mechanism following the biopsy. 2 This change of the cellular and cytokine environment with the subsequent remodeling of the extracellular matrix may have lead to the ultimate resolution of the lesions. 9 To the best of our knowledge, this is the first report of a lichenoid reaction to black tattoos with generalized distribution and spontaneous resolution.…”

“…Generalized tissue reactions are infrequent, and only one case of spontaneous resolution of a granulomatous reaction to a cosmetic lip tattoo has been recorded. 2 Herein, we present the case of a generalized lichenoid reaction to black tattoos that resolved spontaneously. Based on a review of the literature, we believe that this is the first case of such a finding.…”